Multifocal Evanescent White Dot Syndrome-like Phenotypes Associated with Inflammatory and Myopic Choroidal Neovascularization

PURPOSE: To present the observation of multifocal evanescent white dot syndrome (MEWDS)-like phenotypes developing in association with the onset of choroidal neovascularization (CNV) in a series of patients.

METHODS: Patients presenting to tertiary-care centers with MEWDS-like phenotypes and CNV were identified.

RESULTS: Five patients presented for the management of CNV in the context of previous diagnoses of punctate inner choroidopathy (PIC) and/or myopia. In time-periods ranging from 0 days to 12 weeks from the diagnosis of active CNV, MEWDS-like changes were observed. Treatment with anti-VEGF agents were instituted in four cases, in an as-required protocol. 1 patient received systemic steroid.

CONCLUSIONS: The development of MEWDS-like phenotypes in association with CNVM can occur in eyes with either inflammatory or non-inflammatory CNVM, and in those who were or were not treated with anti-VEGF therapy. The association suggests an inflammatory event, which causes RPE changes and probably induces the development of the CNV.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Ocular immunology and inflammation - 30(2022), 7-8 vom: 14. Okt., Seite 1707-1714

Sprache:

Englisch

Beteiligte Personen:

Burke, Tomas R [VerfasserIn]
Addison, Peter K F [VerfasserIn]
Pavesio, Carlos E [VerfasserIn]

Links:

Volltext

Themen:

Autoflurescence
Choroidal neovascularization
Journal Article
Multifocal eveanescent white dot syndrome

Anmerkungen:

Date Completed 15.12.2022

Date Revised 15.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/09273948.2021.1936563

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM326728538