Comparison of the maternal serum endocan levels in preterm premature rupture of membrane and normal pregnancy
© 2021 Japan Society of Obstetrics and Gynecology..
OBJECTIVE: Endocan is a novel marker of endothelial inflammation. In this study, we aimed to show whether there was a significant difference between the endocan levels of pregnant women with and without preterm premature rupture of membranes (PPROM and non-PPROM). Also, we aimed to find a relation between endocan levels and the latent period.
MATERIAL AND METHODS: Pregnant women with PPROM between 28 and 34 weeks of gestation and those without PPROM with similar gestational weeks were included in the study. A total of 88 pregnant women, 44 with PROM and 44 healthy pregnancies, were evaluated. Demographic and obstetric features, leukocyte, and endocan levels of the study and control groups were compared.
RESULTS: The demographic features and obstetric history of both groups were similar. The mean leukocyte and endocan levels of the study group were higher than in the control group (p < 0.001 and 0.029, respectively). The leukocyte level was the only independent factor predicting PPROM after multivariate logistic regression analysis.
CONCLUSION: Although the endocan levels were higher in patients with PPROM, multivariate analysis showed that the only independent predictive factor was the leukocyte level.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:47 |
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| Enthalten in: |
The journal of obstetrics and gynaecology research - 47(2021), 9 vom: 02. Sept., Seite 3151-3158 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
İflazoğlu, Nuray [VerfasserIn] |
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| Links: |
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| Themen: |
Biomarkers |
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| Anmerkungen: |
Date Completed 06.09.2021 Date Revised 06.09.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/jog.14836 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM326577270 |
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| 245 | 1 | 0 | |a Comparison of the maternal serum endocan levels in preterm premature rupture of membrane and normal pregnancy |
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| 500 | |a Date Completed 06.09.2021 | ||
| 500 | |a Date Revised 06.09.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021 Japan Society of Obstetrics and Gynecology. | ||
| 520 | |a OBJECTIVE: Endocan is a novel marker of endothelial inflammation. In this study, we aimed to show whether there was a significant difference between the endocan levels of pregnant women with and without preterm premature rupture of membranes (PPROM and non-PPROM). Also, we aimed to find a relation between endocan levels and the latent period | ||
| 520 | |a MATERIAL AND METHODS: Pregnant women with PPROM between 28 and 34 weeks of gestation and those without PPROM with similar gestational weeks were included in the study. A total of 88 pregnant women, 44 with PROM and 44 healthy pregnancies, were evaluated. Demographic and obstetric features, leukocyte, and endocan levels of the study and control groups were compared | ||
| 520 | |a RESULTS: The demographic features and obstetric history of both groups were similar. The mean leukocyte and endocan levels of the study group were higher than in the control group (p < 0.001 and 0.029, respectively). The leukocyte level was the only independent factor predicting PPROM after multivariate logistic regression analysis | ||
| 520 | |a CONCLUSION: Although the endocan levels were higher in patients with PPROM, multivariate analysis showed that the only independent predictive factor was the leukocyte level | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a endocan levels | |
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| 650 | 4 | |a premature rupture of membrane | |
| 650 | 4 | |a preterm birth | |
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| 700 | 1 | |a Eroğlu, Hasan |e verfasserin |4 aut | |
| 700 | 1 | |a Tolunay, Harun Egemen |e verfasserin |4 aut | |
| 700 | 1 | |a Yücel, Aykan |e verfasserin |4 aut | |
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