High-flow Nasal Cannula therapy : A feasible treatment for vulnerable elderly COVID-19 patients in the wards
Copyright © 2021 Elsevier Inc. All rights reserved..
BACKGROUND: Invasive mechanical ventilation is the treatment of choice in COVID-19 patients when hypoxemia persists, despite maximum conventional oxygen administration. Some frail patients with severe hypoxemic respiratory failure are deemed not eligible for invasive mechanical ventilation.
OBJECTIVES: To investigate whether High-flow nasal cannula (HFNC) in the wards could serve as a rescue therapy in these frail patients.
METHODS: This retrospective cohort study included frail COVID-19 patients admitted to the hospital between March 9th and May 1st 2020. HFNC therapy was started in the wards. The primary endpoint was the survival rate at hospital discharge.
RESULTS: Thirty-two patients with a median age of 79.0 years (74.5-83.0) and a Clinical Frailty Score of 4 out of 9 (3-6) were included. Only 6% reported HFNC tolerability issues. The overall survival rate was 25% at hospital discharge.
CONCLUSIONS: This study suggests that, when preferred, HFNC in the wards could be a potential rescue therapy for respiratory failure in vulnerable COVID-19 patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:50 |
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| Enthalten in: |
Heart & lung : the journal of critical care - 50(2021), 5 vom: 15. Sept., Seite 654-659 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
van Steenkiste, Job [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 04.08.2021 Date Revised 17.12.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.hrtlng.2021.04.008 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM326464239 |
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| 500 | |a Date Revised 17.12.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021 Elsevier Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Invasive mechanical ventilation is the treatment of choice in COVID-19 patients when hypoxemia persists, despite maximum conventional oxygen administration. Some frail patients with severe hypoxemic respiratory failure are deemed not eligible for invasive mechanical ventilation | ||
| 520 | |a OBJECTIVES: To investigate whether High-flow nasal cannula (HFNC) in the wards could serve as a rescue therapy in these frail patients | ||
| 520 | |a METHODS: This retrospective cohort study included frail COVID-19 patients admitted to the hospital between March 9th and May 1st 2020. HFNC therapy was started in the wards. The primary endpoint was the survival rate at hospital discharge | ||
| 520 | |a RESULTS: Thirty-two patients with a median age of 79.0 years (74.5-83.0) and a Clinical Frailty Score of 4 out of 9 (3-6) were included. Only 6% reported HFNC tolerability issues. The overall survival rate was 25% at hospital discharge | ||
| 520 | |a CONCLUSIONS: This study suggests that, when preferred, HFNC in the wards could be a potential rescue therapy for respiratory failure in vulnerable COVID-19 patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Frailty | |
| 650 | 4 | |a High-flow Nasal Cannula | |
| 650 | 4 | |a Intensive care unit | |
| 700 | 1 | |a van Herwerden, Michael C |e verfasserin |4 aut | |
| 700 | 1 | |a Weller, Dolf |e verfasserin |4 aut | |
| 700 | 1 | |a van den Bout, Christiaan J |e verfasserin |4 aut | |
| 700 | 1 | |a Ruiter, Rikje |e verfasserin |4 aut | |
| 700 | 1 | |a den Hollander, Jan G |e verfasserin |4 aut | |
| 700 | 1 | |a El Moussaoui, Rachida |e verfasserin |4 aut | |
| 700 | 1 | |a Verhoeven, Gert T |e verfasserin |4 aut | |
| 700 | 1 | |a van Noord, Charlotte |e verfasserin |4 aut | |
| 700 | 1 | |a van den Dorpel, Marinus A |e verfasserin |4 aut | |
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