Brexanolone to Treat Postpartum Depression in Adult Women

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ZULRESSO (Brexanolone) is a novel FDA-approved treatment for moderate-to-severe postpartum depression. Postpartum depression may be diagnosed in women experiencing depressive symptoms which can manifest as cognitive, behavioral, or emotional disturbances as early as the third trimester to 4 weeks following delivery. The efficacy of brexanolone suggests that neurosteroids such as allopregnanolone are important to treat PPD. However, it is currently unclear if brexanolone provides lasting relief of depressive symptoms at or beyond 30 days following administration. Further studies are necessary to make this determination.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:51

Enthalten in:

Psychopharmacology bulletin - 51(2021), 2 vom: 16. März, Seite 115-130

Sprache:

Englisch

Beteiligte Personen:

Cornett, Elyse M [VerfasserIn]
Rando, Lauren [VerfasserIn]
Labbé, Austin M [VerfasserIn]
Perkins, Wil [VerfasserIn]
Kaye, Adam M [VerfasserIn]
Kaye, Alan David [VerfasserIn]
Viswanath, Omar [VerfasserIn]
Urits, Ivan [VerfasserIn]

Themen:

BXO86P3XXW
Beta-Cyclodextrins
Brexanolone
Drug Combinations
GABA
Journal Article
Major depressive disorder
Postpartum depression
Pregnanolone
Review
ZULRESSO

Anmerkungen:

Date Completed 27.12.2021

Date Revised 11.11.2023

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM326410465