Cardiac Sarcoidosis Is Uncommon in Patients with Isolated Sarcoid Uveitis : Outcome of 294 Cases
Recently, concerns have been raised about an increased risk of cardiac sarcoidosis in patients with sarcoid uveitis. While cardiac sarcoidosis has a high mortality burden, there is still a lack of precise data on this association. The objective of this study is to describe the frequency and type of cardiac complications associated with sarcoidosis of a large cohort of patients with sarcoid uveitis. We analyzed the cardiac outcomes of a monocentric retrospective cohort of consecutive adults with a diagnosis of sarcoid uveitis between January 2004 and March 2020 in a tertiary French university hospital. A total of 294 patients with a final diagnosis of sarcoid uveitis were included. At final follow-up, seven (2.4%) patients of the cohort had cardiac sarcoidosis. Cardiac sarcoidosis was more frequent among patients with previously reported systemic sarcoidosis (p = 0.008). The prevalence of cardiac sarcoidosis among patients with sarcoid uveitis is low, but patients with previously diagnosed sarcoidosis or those who develop systemic sarcoidosis during follow-up appear to be at increased risk.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Journal of clinical medicine - 10(2021), 10 vom: 15. Mai |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Richard, Mael [VerfasserIn] |
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| Anmerkungen: |
Date Revised 05.06.2021 published: Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.3390/jcm10102146 |
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| PPN (Katalog-ID): |
NLM326120416 |
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| 520 | |a Recently, concerns have been raised about an increased risk of cardiac sarcoidosis in patients with sarcoid uveitis. While cardiac sarcoidosis has a high mortality burden, there is still a lack of precise data on this association. The objective of this study is to describe the frequency and type of cardiac complications associated with sarcoidosis of a large cohort of patients with sarcoid uveitis. We analyzed the cardiac outcomes of a monocentric retrospective cohort of consecutive adults with a diagnosis of sarcoid uveitis between January 2004 and March 2020 in a tertiary French university hospital. A total of 294 patients with a final diagnosis of sarcoid uveitis were included. At final follow-up, seven (2.4%) patients of the cohort had cardiac sarcoidosis. Cardiac sarcoidosis was more frequent among patients with previously reported systemic sarcoidosis (p = 0.008). The prevalence of cardiac sarcoidosis among patients with sarcoid uveitis is low, but patients with previously diagnosed sarcoidosis or those who develop systemic sarcoidosis during follow-up appear to be at increased risk | ||
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| 700 | 1 | |a Durel, Cécile-Audrey |e verfasserin |4 aut | |
| 700 | 1 | |a Hot, Arnaud |e verfasserin |4 aut | |
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| 700 | 1 | |a Durieu, Isabelle |e verfasserin |4 aut | |
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| 700 | 1 | |a Kodjikian, Laurent |e verfasserin |4 aut | |
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