Calciphylaxis : Risk Factors and Histologic Findings in a Case Series From a Tertiary Care Referral Hospital
Copyright © 2021 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved..
Recent years have seen important advances in our understanding of calciphylaxis, especially regarding newly identified risk factors and histologic findings that may aid diagnosis. This retrospective study of cases of calciphylaxis treated in our hospital in the last 13 years focuses on newly revealed aspects of this disease. We describe 16 patients (62.5% women; mean age, 67.9 years). In addition to advanced kidney disease (in 75% of our patients), other factors associated with the presence of calciphylaxis were a history of treatments related to phosphorus and calcium metabolism (75%) and anticoagulation (62.5%), usually with vitamin-K antagonists. Histology showed alterations in elastic fibers in only 25% of the biopsy specimens. Eleven of the patients died: sepsis was most often the cause.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2021 |
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| Enthalten in: |
Actas dermo-sifiliograficas - (2021) vom: 30. Apr. |
| Sprache: |
Englisch |
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| Weiterer Titel: |
Calcifilaxis: factores de riesgo y hallazgos histológicos en una serie de casos de un hospital terciario |
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| Beteiligte Personen: |
Sánchez-Pujol, M J [VerfasserIn] |
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| Links: |
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| Themen: |
Acenocoumarol |
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| Anmerkungen: |
Date Revised 22.02.2024 published: Print-Electronic Citation Status Publisher |
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| doi: |
10.1016/j.ad.2020.08.014 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM324930267 |
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| 245 | 1 | 0 | |a Calciphylaxis |b Risk Factors and Histologic Findings in a Case Series From a Tertiary Care Referral Hospital |
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| 520 | |a Copyright © 2021 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a Recent years have seen important advances in our understanding of calciphylaxis, especially regarding newly identified risk factors and histologic findings that may aid diagnosis. This retrospective study of cases of calciphylaxis treated in our hospital in the last 13 years focuses on newly revealed aspects of this disease. We describe 16 patients (62.5% women; mean age, 67.9 years). In addition to advanced kidney disease (in 75% of our patients), other factors associated with the presence of calciphylaxis were a history of treatments related to phosphorus and calcium metabolism (75%) and anticoagulation (62.5%), usually with vitamin-K antagonists. Histology showed alterations in elastic fibers in only 25% of the biopsy specimens. Eleven of the patients died: sepsis was most often the cause | ||
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