Physiological Variables Associated with the Development of Acute Mountain Sickness
Objective To identify the physiological variables associated with the development of acute mountain sickness (AMS).Methods Eighty four young Chinese men residing at low altitude were taken to an altitude of 4000 m within 40 hours. At sea level and at high altitude, we measured the heart rate, blood pressure, and peripheral oxygen saturation (SpO2) respectively. We also collect blood samples from each participants before and after the altitude elevation. The blood routine and biochemical examinations were performed for all blood samples. The revised Lake Louise Criteria was adopted to diagnose AMS after the subjects arrived at the target high altitude. The association between the presence of AMS and subjects' physiological variables were analysed statistically.Results Of 84 participants, 34 (40.5%) developed AMS. Compared with non AMS group, in the AMS group, the percentage of neutrophils was significantly higher (64.5%±11.2% vs. 58.1%±8.8%, P =0.014), while the level of SpO2 was significantly lower (79.4%±5.4% vs. 82.7%±5.6, P=0.008). Binary logistic regression analyses emphasized the association of neutrophils (OR: 1.06, 95% CI: 1.01-1.12, P=0.034) and SpO2 level (OR: 0.87, 95% CI : 0.79-0.95, P=0.004) with the development of AMS.Conclusion The ability to sustain SpO2 after altitude elevation and the increase of neutrophils were associated with the development of AMS in young males.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:34 |
|---|---|
| Enthalten in: |
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 34(2019), 4 vom: 12. Nov., Seite 263-269 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Liu, Chun-Wei [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Altitude sickness |
|---|
| Anmerkungen: |
Date Completed 12.11.2021 Date Revised 12.11.2021 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.24920/003518 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM324601115 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM324601115 | ||
| 003 | DE-627 | ||
| 005 | 20231225190648.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.24920/003518 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1081.xml |
| 035 | |a (DE-627)NLM324601115 | ||
| 035 | |a (NLM)33906712 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Liu, Chun-Wei |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Physiological Variables Associated with the Development of Acute Mountain Sickness |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 12.11.2021 | ||
| 500 | |a Date Revised 12.11.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Objective To identify the physiological variables associated with the development of acute mountain sickness (AMS).Methods Eighty four young Chinese men residing at low altitude were taken to an altitude of 4000 m within 40 hours. At sea level and at high altitude, we measured the heart rate, blood pressure, and peripheral oxygen saturation (SpO2) respectively. We also collect blood samples from each participants before and after the altitude elevation. The blood routine and biochemical examinations were performed for all blood samples. The revised Lake Louise Criteria was adopted to diagnose AMS after the subjects arrived at the target high altitude. The association between the presence of AMS and subjects' physiological variables were analysed statistically.Results Of 84 participants, 34 (40.5%) developed AMS. Compared with non AMS group, in the AMS group, the percentage of neutrophils was significantly higher (64.5%±11.2% vs. 58.1%±8.8%, P =0.014), while the level of SpO2 was significantly lower (79.4%±5.4% vs. 82.7%±5.6, P=0.008). Binary logistic regression analyses emphasized the association of neutrophils (OR: 1.06, 95% CI: 1.01-1.12, P=0.034) and SpO2 level (OR: 0.87, 95% CI : 0.79-0.95, P=0.004) with the development of AMS.Conclusion The ability to sustain SpO2 after altitude elevation and the increase of neutrophils were associated with the development of AMS in young males | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a altitude sickness | |
| 650 | 4 | |a hypoxia | |
| 650 | 4 | |a physiology | |
| 650 | 7 | |a Oxygen |2 NLM | |
| 650 | 7 | |a S88TT14065 |2 NLM | |
| 700 | 1 | |a Li, Zong-Bin |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Shi, Ya-Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Jin-Li |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Yun-Dai |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih |d 1996 |g 34(2019), 4 vom: 12. Nov., Seite 263-269 |w (DE-627)NLM012606545 |x 1001-9294 |7 nnns |
| 773 | 1 | 8 | |g volume:34 |g year:2019 |g number:4 |g day:12 |g month:11 |g pages:263-269 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.24920/003518 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 34 |j 2019 |e 4 |b 12 |c 11 |h 263-269 | ||