Batch injection analysis with amperometric detection for fluoroquinolone determination in urine, pharmaceutical formulations, and milk samples using a reduced graphene oxide-modified glassy carbon electrode
© 2021. Springer-Verlag GmbH Germany, part of Springer Nature..
In this work, the batch injection analysis system with amperometric detection using reduced graphene oxide as a modifier of glassy carbon electrode (GCE) was investigated for the simple, fast, and sensitive monitoring of levofloxacin (LEVO) and ciprofloxacin (CIPRO) in samples of pharmaceutical formulations, synthetic urine, and milk (low- and high-fat content). LEVO and CIPRO were quantified in seven samples using amperometric measurements at +1.10 V vs Ag/AgCl, KCl(sat). The developed methods showed excellent analytical performance with limits of detection of 0.30 and 0.16 μmol L-1, linear range from 3.0 to 50 μmol L-1 and 1.0 to 50 μmol L-1, relative standard deviation below 9.7 and 3.1%, and recovery ranges ranging from 80 to 107% and from 78 to 109% for LEVO and CIPRO, respectively. In addition, the minimum sample preparation (simple dilution) combined with a high analytical frequency (130 to 180 analyses per hour) can be highlighted. Thus, the methods are promising for implementation in routine analysis and quality control to different samples.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:414 |
|---|---|
| Enthalten in: |
Analytical and bioanalytical chemistry - 414(2022), 18 vom: 27. Juli, Seite 5309-5318 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
de Faria, Lucas Vinícius [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
5E8K9I0O4U |
|---|
| Anmerkungen: |
Date Completed 01.07.2022 Date Revised 01.07.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1007/s00216-021-03342-3 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM324439385 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM324439385 | ||
| 003 | DE-627 | ||
| 005 | 20231225190327.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00216-021-03342-3 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1081.xml |
| 035 | |a (DE-627)NLM324439385 | ||
| 035 | |a (NLM)33890118 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a de Faria, Lucas Vinícius |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Batch injection analysis with amperometric detection for fluoroquinolone determination in urine, pharmaceutical formulations, and milk samples using a reduced graphene oxide-modified glassy carbon electrode |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 01.07.2022 | ||
| 500 | |a Date Revised 01.07.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021. Springer-Verlag GmbH Germany, part of Springer Nature. | ||
| 520 | |a In this work, the batch injection analysis system with amperometric detection using reduced graphene oxide as a modifier of glassy carbon electrode (GCE) was investigated for the simple, fast, and sensitive monitoring of levofloxacin (LEVO) and ciprofloxacin (CIPRO) in samples of pharmaceutical formulations, synthetic urine, and milk (low- and high-fat content). LEVO and CIPRO were quantified in seven samples using amperometric measurements at +1.10 V vs Ag/AgCl, KCl(sat). The developed methods showed excellent analytical performance with limits of detection of 0.30 and 0.16 μmol L-1, linear range from 3.0 to 50 μmol L-1 and 1.0 to 50 μmol L-1, relative standard deviation below 9.7 and 3.1%, and recovery ranges ranging from 80 to 107% and from 78 to 109% for LEVO and CIPRO, respectively. In addition, the minimum sample preparation (simple dilution) combined with a high analytical frequency (130 to 180 analyses per hour) can be highlighted. Thus, the methods are promising for implementation in routine analysis and quality control to different samples | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Batch injection analysis | |
| 650 | 4 | |a Fluoroquinolones | |
| 650 | 4 | |a Milk | |
| 650 | 4 | |a Pharmaceutical formulations | |
| 650 | 4 | |a Reduced graphene oxide sensor | |
| 650 | 4 | |a Urine | |
| 650 | 7 | |a Fluoroquinolones |2 NLM | |
| 650 | 7 | |a graphene oxide |2 NLM | |
| 650 | 7 | |a Ciprofloxacin |2 NLM | |
| 650 | 7 | |a 5E8K9I0O4U |2 NLM | |
| 650 | 7 | |a Carbon |2 NLM | |
| 650 | 7 | |a 7440-44-0 |2 NLM | |
| 650 | 7 | |a Graphite |2 NLM | |
| 650 | 7 | |a 7782-42-5 |2 NLM | |
| 700 | 1 | |a de Farias, Davi Marques |e verfasserin |4 aut | |
| 700 | 1 | |a Lisboa, Thalles Pedrosa |e verfasserin |4 aut | |
| 700 | 1 | |a Matos, Maria Auxiliadora Costa |e verfasserin |4 aut | |
| 700 | 1 | |a Munoz, Rodrigo Alejandro Abarza |e verfasserin |4 aut | |
| 700 | 1 | |a Matos, Renato Camargo |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Analytical and bioanalytical chemistry |d 1995 |g 414(2022), 18 vom: 27. Juli, Seite 5309-5318 |w (DE-627)NLM118176722 |x 1618-2650 |7 nnns |
| 773 | 1 | 8 | |g volume:414 |g year:2022 |g number:18 |g day:27 |g month:07 |g pages:5309-5318 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00216-021-03342-3 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 414 |j 2022 |e 18 |b 27 |c 07 |h 5309-5318 | ||