Pharmacist-Directed Self-Management of Blood Pressure Versus Conventional Management in Patients with Hypertension : A Randomized Control Trial

INTRODUCTION: Data has shown that pharmacist-directed health services play a key role in the treatment of hypertension.

AIM: We aimed to perform this study to compare two methods of the pharmacist-directed home blood pressure monitoring (HBPM) and the usual care.

METHODS: A total of 126 patients with uncontrolled blood pressure (BP) were randomized 1:1 into the pharmacist-directed HBPM and the usual care groups. In the intervention group, the patients were trained to measure their BPs and adjust their medications based on the designed protocol under the supervision of a clinical pharmacist. The primary endpoint of the study was the comparison of the BPs at baseline and months 1, 3, and 6.

RESULTS: One month after the allocation, the baseline systolic BP (SBP) (150.5 ± 13.1 vs. 149.7 ± 11.2 mm Hg; P = 0.71) and diastolic BP (DBP) (97.2 ± 9.8 vs. 93.6 ± 14.5; P = 0.11) significantly dropped to the control range equally in 85.2% of the patients in two groups (SBP: 128.8 ± 6.4 vs. 125.6 ± 7.1 mm Hg; P = 0.01 and DBP: 89.1 ± 6.2 vs. 81.5 ± 6.0 mm Hg; P = 0.01). This pattern continued during the study period (month 6; SBP: 115.6 ± 10.1vs. 116.1 ± 9.6 mm Hg; P = 0.78; DBP: 79.0 ± 5.0 vs. 77.2 ± 5.8 mm Hg; P = 0.08).

CONCLUSIONS: In this study, we did not observe any significant difference between the pharmacist-directed HBPM and usual care methods in decreasing BP.

Media Type:

Electronic Article

Year of Publication:

2021

Contained In:

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension - Vol. 28, No. 3 (2021), p. 283-290

Language:

English

Contributors:

Khiali, Sajad
Khezerlo-Aghdam, Naser
Namdar, Hossein
Entezari-Maleki, Taher

Links:

Volltext

Keywords:

*Blood Pressure Monitoring, Ambulatory
*Self-Management
Adult
Aged
Antihypertensive Agents
Blood Pressure
Blood pressure
Blood pressure control
Home blood pressure monitoring
Humans
Hypertension
Journal Article
Middle Aged
Pharmacist-directed health service
Pharmacists
Randomized Controlled Trial

Notes:

Date Completed 24.06.2021

Date Revised 24.06.2021

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1007/s40292-021-00445-x

PMID:

33765257

PPN (Catalogue-ID):

NLM324298943