The role of serum salusin alpha and beta levels and atherosclerotic risk factors in idiopathic sudden hearing loss pathogenesis
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..
PURPOSE: The aim of this study was to investigate the importance of atherosclerosis in the pathogenesis of sudden hearing loss by evaluating the newly discovered markers, serum salusin-α and salusin-β. We also aimed to evaluate atherosclerosis risk factors, such as lipid profile, smoking, body mass index, waist circumference and mean blood pressure of the patients.
METHODS: Fifty-two patients diagnosed with sudden hearing loss (study group) and fifty healthy people (control group) were included in the study. Detailed history was taken from the patients and risk factors for atherosclerosis, such as smoking, body mass index, waist circumference, lipid profile, mean blood pressure and serum salusin-α and salusin-β levels, were evaluated. The study group was divided into recovery group (subgroup I) and non-recovery group (subgroup II).
RESULTS: The salusin-β median value was found to be significantly higher in the study group compared to the control group (p < 0.05). The salusin-β median value was found to be significantly higher in subgroup 2 and was found to be a poor prognostic factor (p < 0.05).
CONCLUSION: From the results obtained in this study, it is thought that salusin-β peptide is increased in patients with sudden hearing loss and it can be evaluated as a poor prognostic factor.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:279 |
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| Enthalten in: |
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 279(2022), 3 vom: 01. März, Seite 1311-1316 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Genç Elden, Sena [VerfasserIn] |
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| Links: |
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| Themen: |
Atherosclerosis |
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| Anmerkungen: |
Date Completed 08.03.2022 Date Revised 08.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00405-021-06804-7 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM324250967 |
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| 245 | 1 | 4 | |a The role of serum salusin alpha and beta levels and atherosclerotic risk factors in idiopathic sudden hearing loss pathogenesis |
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| 500 | |a Date Revised 08.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. | ||
| 520 | |a PURPOSE: The aim of this study was to investigate the importance of atherosclerosis in the pathogenesis of sudden hearing loss by evaluating the newly discovered markers, serum salusin-α and salusin-β. We also aimed to evaluate atherosclerosis risk factors, such as lipid profile, smoking, body mass index, waist circumference and mean blood pressure of the patients | ||
| 520 | |a METHODS: Fifty-two patients diagnosed with sudden hearing loss (study group) and fifty healthy people (control group) were included in the study. Detailed history was taken from the patients and risk factors for atherosclerosis, such as smoking, body mass index, waist circumference, lipid profile, mean blood pressure and serum salusin-α and salusin-β levels, were evaluated. The study group was divided into recovery group (subgroup I) and non-recovery group (subgroup II) | ||
| 520 | |a RESULTS: The salusin-β median value was found to be significantly higher in the study group compared to the control group (p < 0.05). The salusin-β median value was found to be significantly higher in subgroup 2 and was found to be a poor prognostic factor (p < 0.05) | ||
| 520 | |a CONCLUSION: From the results obtained in this study, it is thought that salusin-β peptide is increased in patients with sudden hearing loss and it can be evaluated as a poor prognostic factor | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Atherosclerosis | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Salusin alpha | |
| 650 | 4 | |a Salusin beta | |
| 650 | 4 | |a Sudden hearing loss | |
| 650 | 7 | |a Biomarkers |2 NLM | |
| 650 | 7 | |a Intercellular Signaling Peptides and Proteins |2 NLM | |
| 700 | 1 | |a Yılmaz, Mahmut Sinan |e verfasserin |4 aut | |
| 700 | 1 | |a Altındiş, Mustafa |e verfasserin |4 aut | |
| 700 | 1 | |a Köroğlu, Mehmet |e verfasserin |4 aut | |
| 700 | 1 | |a Elden, Halil |e verfasserin |4 aut | |
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