Severe Acute Respiratory Syndrome Coronavirus 2 Transmission in a Georgia School District-United States, December 2020-January 2021
Published by Oxford University Press for the Infectious Diseases Society of America 2021..
BACKGROUND: To inform prevention strategies, we assessed the extent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and settings in which transmission occurred in a Georgia public school district.
METHODS: During 1 December 2020-22 January 2021, SARS-CoV-2-infected index cases and their close contacts in schools were identified by school and public health officials. For in-school contacts, we assessed symptoms and offered SARS-CoV-2 reverse-transcription polymerase chain reaction (RT-PCR) testing; performed epidemiologic investigations and whole-genome sequencing to identify in-school transmission; and calculated secondary attack rate (SAR) by school setting (eg, sports, elementary school classroom), index case role (ie, staff, student), and index case symptomatic status.
RESULTS: We identified 86 index cases and 1119 contacts, 688 (61.5%) of whom received testing. Fifty-nine of 679 (8.7%) contacts tested positive; 15 of 86 (17.4%) index cases resulted in ≥2 positive contacts. Among 55 persons testing positive with available symptom data, 31 (56.4%) were asymptomatic. Highest SARs were in indoor, high-contact sports settings (23.8% [95% confidence interval {CI}, 12.7%-33.3%]), staff meetings/lunches (18.2% [95% CI, 4.5%-31.8%]), and elementary school classrooms (9.5% [95% CI, 6.5%-12.5%]). The SAR was higher for staff (13.1% [95% CI, 9.0%-17.2%]) vs student index cases (5.8% [95% CI, 3.6%-8.0%]) and for symptomatic (10.9% [95% CI, 8.1%-13.9%]) vs asymptomatic index cases (3.0% [95% CI, 1.0%-5.5%]).
CONCLUSIONS: Indoor sports may pose a risk to the safe operation of in-person learning. Preventing infection in staff members, through measures that include coronavirus disease 2019 vaccination, is critical to reducing in-school transmission. Because many positive contacts were asymptomatic, contact tracing should be paired with testing, regardless of symptoms.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:74 |
|---|---|
| Enthalten in: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 74(2022), 2 vom: 29. Jan., Seite 319-326 |
| Sprache: |
Englisch |
|---|
| Links: |
|---|
| Themen: |
COVID-19 |
|---|
| Anmerkungen: |
Date Completed 02.02.2022 Date Revised 02.02.2022 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.1093/cid/ciab332 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM324190565 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM324190565 | ||
| 003 | DE-627 | ||
| 005 | 20231225185804.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1093/cid/ciab332 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1080.xml |
| 035 | |a (DE-627)NLM324190565 | ||
| 035 | |a (NLM)33864375 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Gettings, Jenna R |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Severe Acute Respiratory Syndrome Coronavirus 2 Transmission in a Georgia School District-United States, December 2020-January 2021 |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 02.02.2022 | ||
| 500 | |a Date Revised 02.02.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Published by Oxford University Press for the Infectious Diseases Society of America 2021. | ||
| 520 | |a BACKGROUND: To inform prevention strategies, we assessed the extent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and settings in which transmission occurred in a Georgia public school district | ||
| 520 | |a METHODS: During 1 December 2020-22 January 2021, SARS-CoV-2-infected index cases and their close contacts in schools were identified by school and public health officials. For in-school contacts, we assessed symptoms and offered SARS-CoV-2 reverse-transcription polymerase chain reaction (RT-PCR) testing; performed epidemiologic investigations and whole-genome sequencing to identify in-school transmission; and calculated secondary attack rate (SAR) by school setting (eg, sports, elementary school classroom), index case role (ie, staff, student), and index case symptomatic status | ||
| 520 | |a RESULTS: We identified 86 index cases and 1119 contacts, 688 (61.5%) of whom received testing. Fifty-nine of 679 (8.7%) contacts tested positive; 15 of 86 (17.4%) index cases resulted in ≥2 positive contacts. Among 55 persons testing positive with available symptom data, 31 (56.4%) were asymptomatic. Highest SARs were in indoor, high-contact sports settings (23.8% [95% confidence interval {CI}, 12.7%-33.3%]), staff meetings/lunches (18.2% [95% CI, 4.5%-31.8%]), and elementary school classrooms (9.5% [95% CI, 6.5%-12.5%]). The SAR was higher for staff (13.1% [95% CI, 9.0%-17.2%]) vs student index cases (5.8% [95% CI, 3.6%-8.0%]) and for symptomatic (10.9% [95% CI, 8.1%-13.9%]) vs asymptomatic index cases (3.0% [95% CI, 1.0%-5.5%]) | ||
| 520 | |a CONCLUSIONS: Indoor sports may pose a risk to the safe operation of in-person learning. Preventing infection in staff members, through measures that include coronavirus disease 2019 vaccination, is critical to reducing in-school transmission. Because many positive contacts were asymptomatic, contact tracing should be paired with testing, regardless of symptoms | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a infection control | |
| 650 | 4 | |a physical distancing | |
| 650 | 4 | |a schools | |
| 700 | 1 | |a Gold, Jeremy A W |e verfasserin |4 aut | |
| 700 | 1 | |a Kimball, Anne |e verfasserin |4 aut | |
| 700 | 1 | |a Forsberg, Kaitlin |e verfasserin |4 aut | |
| 700 | 1 | |a Scott, Colleen |e verfasserin |4 aut | |
| 700 | 1 | |a Uehara, Anna |e verfasserin |4 aut | |
| 700 | 1 | |a Tong, Suxiang |e verfasserin |4 aut | |
| 700 | 1 | |a Hast, Marisa |e verfasserin |4 aut | |
| 700 | 1 | |a Swanson, Megan R |e verfasserin |4 aut | |
| 700 | 1 | |a Morris, Elana |e verfasserin |4 aut | |
| 700 | 1 | |a Oraka, Emeka |e verfasserin |4 aut | |
| 700 | 1 | |a Almendares, Olivia |e verfasserin |4 aut | |
| 700 | 1 | |a Thomas, Ebony S |e verfasserin |4 aut | |
| 700 | 1 | |a Mehari, Lemlem |e verfasserin |4 aut | |
| 700 | 1 | |a McCloud, Jazmyn |e verfasserin |4 aut | |
| 700 | 1 | |a Roberts, Gurleen |e verfasserin |4 aut | |
| 700 | 1 | |a Crosby, Deanna |e verfasserin |4 aut | |
| 700 | 1 | |a Balajee, Abirami |e verfasserin |4 aut | |
| 700 | 1 | |a Burnett, Eleanor |e verfasserin |4 aut | |
| 700 | 1 | |a Chancey, Rebecca J |e verfasserin |4 aut | |
| 700 | 1 | |a Cook, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Donadel, Morgane |e verfasserin |4 aut | |
| 700 | 1 | |a Espinosa, Catherine |e verfasserin |4 aut | |
| 700 | 1 | |a Evans, Mary E |e verfasserin |4 aut | |
| 700 | 1 | |a Fleming-Dutra, Katherine E |e verfasserin |4 aut | |
| 700 | 1 | |a Forero, Catalina |e verfasserin |4 aut | |
| 700 | 1 | |a Kukielka, Esther A |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yan |e verfasserin |4 aut | |
| 700 | 1 | |a Marcet, Paula L |e verfasserin |4 aut | |
| 700 | 1 | |a Mitruka, Kiren |e verfasserin |4 aut | |
| 700 | 1 | |a Nakayama, Jasmine Y |e verfasserin |4 aut | |
| 700 | 1 | |a Nakazawa, Yoshinori |e verfasserin |4 aut | |
| 700 | 1 | |a O'Hegarty, Michelle |e verfasserin |4 aut | |
| 700 | 1 | |a Pratt, Caroline |e verfasserin |4 aut | |
| 700 | 1 | |a Rice, Marion E |e verfasserin |4 aut | |
| 700 | 1 | |a Rodriguez Stewart, Roxana M |e verfasserin |4 aut | |
| 700 | 1 | |a Sabogal, Raquel |e verfasserin |4 aut | |
| 700 | 1 | |a Sanchez, Emanny |e verfasserin |4 aut | |
| 700 | 1 | |a Velasco-Villa, Andres |e verfasserin |4 aut | |
| 700 | 1 | |a Weng, Mark K |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Jing |e verfasserin |4 aut | |
| 700 | 1 | |a Rivera, Grant |e verfasserin |4 aut | |
| 700 | 1 | |a Parrott, Tonia |e verfasserin |4 aut | |
| 700 | 1 | |a Franklin, Rachel |e verfasserin |4 aut | |
| 700 | 1 | |a Memark, Janet |e verfasserin |4 aut | |
| 700 | 1 | |a Drenzek, Cherie |e verfasserin |4 aut | |
| 700 | 1 | |a Hall, Aron J |e verfasserin |4 aut | |
| 700 | 1 | |a Kirking, Hannah L |e verfasserin |4 aut | |
| 700 | 1 | |a Tate, Jacqueline E |e verfasserin |4 aut | |
| 700 | 1 | |a Vallabhaneni, Snigdha |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |d 1992 |g 74(2022), 2 vom: 29. Jan., Seite 319-326 |w (DE-627)NLM012603007 |x 1537-6591 |7 nnns |
| 773 | 1 | 8 | |g volume:74 |g year:2022 |g number:2 |g day:29 |g month:01 |g pages:319-326 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1093/cid/ciab332 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 74 |j 2022 |e 2 |b 29 |c 01 |h 319-326 | ||