Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment
Copyright® by the International Brazilian Journal of Urology..
INTRODUCTION: Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in postnatal stages is preventable given adequate evaluation, follow-up and proactive management. The aim of this document is to update issues on medical management of neurogenic bladder in children.
MATERIALS AND METHODS: Five Pediatric Urologists joined a group of experts and reviewed all important issues on "Spina Bifida, Neurogenic Bladder in Children" and elaborated a draft of the document. All the members of the group focused on the same system of classification of the levels of evidence (GRADE system) in order to assess the literature and the recommendations. During the year 2020 the panel of experts has met virtually to review, discuss and write a consensus document.
RESULTS AND DISCUSSION: The panel addressed recommendations on up to date choice of diagnosis evaluation and therapies. Clean intermittent catheterization (CIC) should be implemented during the first days of life, and antimuscarinic drugs should be indicated upon results of urodynamic studies. When the patient becomes refractory to first-line therapy, receptor-selective pharmacotherapy is available nowadays, which leads to a reduction in reconstructive procedures, such as augmentation cystoplasty.
| Errataetall: |
CommentIn: Int Braz J Urol. 2022 Jan-Feb;48(1):52-53. - PMID 34735081 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:48 |
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| Enthalten in: |
International braz j urol : official journal of the Brazilian Society of Urology - 48(2022), 1 vom: 04. Jan., Seite 31-51 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sager, Cristian [VerfasserIn] |
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| Links: |
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| Themen: |
Child |
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| Anmerkungen: |
Date Completed 06.12.2021 Date Revised 25.12.2021 published: Print CommentIn: Int Braz J Urol. 2022 Jan-Feb;48(1):52-53. - PMID 34735081 Citation Status MEDLINE |
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| doi: |
10.1590/S1677-5538.IBJU.2020.0989 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 500 | |a CommentIn: Int Braz J Urol. 2022 Jan-Feb;48(1):52-53. - PMID 34735081 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright® by the International Brazilian Journal of Urology. | ||
| 520 | |a INTRODUCTION: Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in postnatal stages is preventable given adequate evaluation, follow-up and proactive management. The aim of this document is to update issues on medical management of neurogenic bladder in children | ||
| 520 | |a MATERIALS AND METHODS: Five Pediatric Urologists joined a group of experts and reviewed all important issues on "Spina Bifida, Neurogenic Bladder in Children" and elaborated a draft of the document. All the members of the group focused on the same system of classification of the levels of evidence (GRADE system) in order to assess the literature and the recommendations. During the year 2020 the panel of experts has met virtually to review, discuss and write a consensus document | ||
| 520 | |a RESULTS AND DISCUSSION: The panel addressed recommendations on up to date choice of diagnosis evaluation and therapies. Clean intermittent catheterization (CIC) should be implemented during the first days of life, and antimuscarinic drugs should be indicated upon results of urodynamic studies. When the patient becomes refractory to first-line therapy, receptor-selective pharmacotherapy is available nowadays, which leads to a reduction in reconstructive procedures, such as augmentation cystoplasty | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
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| 650 | 4 | |a Therapy [Subheading] | |
| 650 | 4 | |a Urinary Bladder, Neurogenic | |
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| 700 | 1 | |a Ormaechea, Edurne |e verfasserin |4 aut | |
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