Ten things you need to know about intensive care unit management of mechanically ventilated patients with COVID-19

Introduction: The ongoing pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has posed important challenges for clinicians and health-care systems worldwide.Areas covered: The aim of this manuscript is to provide brief guidance for intensive care unit management of mechanically ventilated patients with COVID-19 based on the literature and our direct experience with this population. PubMed, EBSCO, and the Cochrane Library were searched up until 15th of January 2021 for relevant literature.Expert opinion: Initially, the respiratory management of COVID-19 relied on the general therapeutic principles for acute respiratory distress syndrome; however, recent findings have suggested that the pathophysiology of hypoxemia in patients with COVID-19 presents specific features and changes over time. Several therapies, including antiviral and anti-inflammatory agents, have been proposed recently. The optimal intensive care unit management of patients with COVID-19 remains unclear; therefore, ongoing and future clinical trials are warranted to clarify the optimal strategies to adopt in this cohort of patients.

Media Type:

Electronic Article

Year of Publication:

2021

Contained In:

Expert review of respiratory medicine - (06.04.2021), p. 1-10

Language:

English

Contributors:

Robba, Chiara
Battaglini, Denise
Ball, Lorenzo
Pelosi, Paolo
Rocco, Patricia R M

Links:

Volltext

Keywords:

Antibiotic therapy
Anticoagulation
Corticosteroids
Journal Article
Mechanical ventilation
Severe acute respiratory syndrome coronavirus-2

Notes:

Date Revised 14.04.2021

published: Print-Electronic

Citation Status Publisher

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1080/17476348.2021.1906226

PMID:

33734900

PPN (Catalogue-ID):

NLM323997406