If it ain't broke don't fix it : Lack of review of antimicrobials in 'well' patients - time for a CRP change
© Royal College of Physicians 2021. All rights reserved..
INTRODUCTION: The rising prevalence of multi-resistant organisms threatens the efficacy of current antimicrobial treatments. Antibiotic stewardship is a key factor in slowing the development of resistance and must become part of a clinician's regular practice. National guidance unanimously emphasises the importance of a 48-hour review of antimicrobial prescriptions. We assessed the compliance of antibiotic reviews across two sites in Wales.
METHOD: Two cycles of data were retrospectively collected across two teaching hospitals in Wales prior and following introduction of an antimicrobial alert sticker. A univariate odds ratio for 48-hour referral stratified by C-reactive protein (CRP) was calculated in a logistic regression model for the cycle one data.
RESULTS: One-hundred and thirty-nine patients were included in the cycle 1 data across both sites. We identified that patients with a CRP ≤100 mg/L (a marker of less severe infection) were less likely to have their antibiotic prescription reviewed by 48 hours.
DISCUSSION: Patients with CRP ≤100 mg/L were less likely to receive a 48-hour review of their antimicrobial prescription. Compliance with review improved following introduction of a simple alert measure.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:8 |
|---|---|
| Enthalten in: |
Future healthcare journal - 8(2021), 1 vom: 17. März, Seite e92-e95 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Hill, Amanda [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Antibiotic resistance |
|---|
| Anmerkungen: |
Date Revised 26.04.2024 published: Print Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.7861/fhj.2019-0042 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM32347134X |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM32347134X | ||
| 003 | DE-627 | ||
| 005 | 20240426232917.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.7861/fhj.2019-0042 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1388.xml |
| 035 | |a (DE-627)NLM32347134X | ||
| 035 | |a (NLM)33791484 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Hill, Amanda |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a If it ain't broke don't fix it |b Lack of review of antimicrobials in 'well' patients - time for a CRP change |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 26.04.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © Royal College of Physicians 2021. All rights reserved. | ||
| 520 | |a INTRODUCTION: The rising prevalence of multi-resistant organisms threatens the efficacy of current antimicrobial treatments. Antibiotic stewardship is a key factor in slowing the development of resistance and must become part of a clinician's regular practice. National guidance unanimously emphasises the importance of a 48-hour review of antimicrobial prescriptions. We assessed the compliance of antibiotic reviews across two sites in Wales | ||
| 520 | |a METHOD: Two cycles of data were retrospectively collected across two teaching hospitals in Wales prior and following introduction of an antimicrobial alert sticker. A univariate odds ratio for 48-hour referral stratified by C-reactive protein (CRP) was calculated in a logistic regression model for the cycle one data | ||
| 520 | |a RESULTS: One-hundred and thirty-nine patients were included in the cycle 1 data across both sites. We identified that patients with a CRP ≤100 mg/L (a marker of less severe infection) were less likely to have their antibiotic prescription reviewed by 48 hours | ||
| 520 | |a DISCUSSION: Patients with CRP ≤100 mg/L were less likely to receive a 48-hour review of their antimicrobial prescription. Compliance with review improved following introduction of a simple alert measure | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a CRP | |
| 650 | 4 | |a antibiotic resistance | |
| 650 | 4 | |a antibiotic review | |
| 650 | 4 | |a antibiotic stewardship | |
| 650 | 4 | |a antimicrobial resistance | |
| 700 | 1 | |a Hamon, Eloise |e verfasserin |4 aut | |
| 700 | 1 | |a Nana, Melanie |e verfasserin |4 aut | |
| 700 | 1 | |a Price, Sian |e verfasserin |4 aut | |
| 700 | 1 | |a Craine, Noel |e verfasserin |4 aut | |
| 700 | 1 | |a Healy, Brendan |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Future healthcare journal |d 2017 |g 8(2021), 1 vom: 17. März, Seite e92-e95 |w (DE-627)NLM297170120 |x 2514-6645 |7 nnns |
| 773 | 1 | 8 | |g volume:8 |g year:2021 |g number:1 |g day:17 |g month:03 |g pages:e92-e95 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.7861/fhj.2019-0042 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 8 |j 2021 |e 1 |b 17 |c 03 |h e92-e95 | ||