Pharmacist-Directed Self-Management of Blood Pressure Versus Conventional Management in Patients with Hypertension : A Randomized Control Trial
INTRODUCTION: Data has shown that pharmacist-directed health services play a key role in the treatment of hypertension.
AIM: We aimed to perform this study to compare two methods of the pharmacist-directed home blood pressure monitoring (HBPM) and the usual care.
METHODS: A total of 126 patients with uncontrolled blood pressure (BP) were randomized 1:1 into the pharmacist-directed HBPM and the usual care groups. In the intervention group, the patients were trained to measure their BPs and adjust their medications based on the designed protocol under the supervision of a clinical pharmacist. The primary endpoint of the study was the comparison of the BPs at baseline and months 1, 3, and 6.
RESULTS: One month after the allocation, the baseline systolic BP (SBP) (150.5 ± 13.1 vs. 149.7 ± 11.2 mm Hg; P = 0.71) and diastolic BP (DBP) (97.2 ± 9.8 vs. 93.6 ± 14.5; P = 0.11) significantly dropped to the control range equally in 85.2% of the patients in two groups (SBP: 128.8 ± 6.4 vs. 125.6 ± 7.1 mm Hg; P = 0.01 and DBP: 89.1 ± 6.2 vs. 81.5 ± 6.0 mm Hg; P = 0.01). This pattern continued during the study period (month 6; SBP: 115.6 ± 10.1vs. 116.1 ± 9.6 mm Hg; P = 0.78; DBP: 79.0 ± 5.0 vs. 77.2 ± 5.8 mm Hg; P = 0.08).
CONCLUSIONS: In this study, we did not observe any significant difference between the pharmacist-directed HBPM and usual care methods in decreasing BP.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
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Enthalten in: |
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension - 28(2021), 3 vom: 25. Mai, Seite 283-290 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Khiali, Sajad [VerfasserIn] |
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Links: |
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Themen: |
Antihypertensive Agents |
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Anmerkungen: |
Date Completed 24.06.2021 Date Revised 24.06.2021 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1007/s40292-021-00445-x |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM323212093 |
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500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a INTRODUCTION: Data has shown that pharmacist-directed health services play a key role in the treatment of hypertension | ||
520 | |a AIM: We aimed to perform this study to compare two methods of the pharmacist-directed home blood pressure monitoring (HBPM) and the usual care | ||
520 | |a METHODS: A total of 126 patients with uncontrolled blood pressure (BP) were randomized 1:1 into the pharmacist-directed HBPM and the usual care groups. In the intervention group, the patients were trained to measure their BPs and adjust their medications based on the designed protocol under the supervision of a clinical pharmacist. The primary endpoint of the study was the comparison of the BPs at baseline and months 1, 3, and 6 | ||
520 | |a RESULTS: One month after the allocation, the baseline systolic BP (SBP) (150.5 ± 13.1 vs. 149.7 ± 11.2 mm Hg; P = 0.71) and diastolic BP (DBP) (97.2 ± 9.8 vs. 93.6 ± 14.5; P = 0.11) significantly dropped to the control range equally in 85.2% of the patients in two groups (SBP: 128.8 ± 6.4 vs. 125.6 ± 7.1 mm Hg; P = 0.01 and DBP: 89.1 ± 6.2 vs. 81.5 ± 6.0 mm Hg; P = 0.01). This pattern continued during the study period (month 6; SBP: 115.6 ± 10.1vs. 116.1 ± 9.6 mm Hg; P = 0.78; DBP: 79.0 ± 5.0 vs. 77.2 ± 5.8 mm Hg; P = 0.08) | ||
520 | |a CONCLUSIONS: In this study, we did not observe any significant difference between the pharmacist-directed HBPM and usual care methods in decreasing BP | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Randomized Controlled Trial | |
650 | 4 | |a Blood pressure | |
650 | 4 | |a Blood pressure control | |
650 | 4 | |a Home blood pressure monitoring | |
650 | 4 | |a Hypertension | |
650 | 4 | |a Pharmacist-directed health service | |
650 | 7 | |a Antihypertensive Agents |2 NLM | |
700 | 1 | |a Khezerlo-Aghdam, Naser |e verfasserin |4 aut | |
700 | 1 | |a Namdar, Hossein |e verfasserin |4 aut | |
700 | 1 | |a Entezari-Maleki, Taher |e verfasserin |4 aut | |
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