30-Day Mortality Rate in Hip Fractures Among the Elderly with Coexistent COVID-19 Infection : A Systematic Review
© Indian Orthopaedics Association 2021..
PURPOSE: Hip fractures in the elderly require a multi-disciplinary approach and are associated with increased morbidity and mortality. The current COVID-19 pandemic has affected substantially this high-risk population group. This present review was done to ascertain whether or not the pandemic has affected the 30-day mortality and outcomes of hip fracture in the elderly.
RESEARCH QUESTION: Does the coexistence of COVID-19 infection and hip fractures in the elderly increase the mortality rates?.
METHODOLOGY: A systematic review and meta-analysis were conducted using three databases (PubMed, EMBASE and SCOPUS) to compare the mortality rates between COVID-19 positive/suspect and COVID-19 negative patients. The secondary outcomes included comparison of in-hospital mortality, complication rate and length of hospital stay. Risk of bias assessment was done using the MINORS tool.
RESULTS: The present review included 20 studies. Primary outcome: A significantly higher 30 day mortality rate was seen in COVID-19 positive/suspect patients with an Odds ratio of 6.09 (95% CI 4.75-8.59, p < 0.00001). Secondary outcome: We observed significantly higher rates of inpatient mortality [OR 18.22, (95% CI 7.10-46.75], complication rate (OR 9.28, 95% CI 4.46-19.30), and length of hospital stay (MD: 4.96, 95% CI 2.86-7.05) in COVID-19 positive/suspect patients as compared to COVID-19 negative patients.
CONCLUSION: COVID-19 has deteriorated the outcomes in elderly patients with hip fractures and associated with higher rates of mortality in the short term. A multidisciplinary approach is needed to contain this "pandemic within a pandemic" and improve the overall outcome to survival.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:55 |
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| Enthalten in: |
Indian journal of orthopaedics - 55(2021), 3 vom: 15. Juni, Seite 571-581 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kumar, Prasoon [VerfasserIn] |
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| Links: |
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| Themen: |
30 day mortality |
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| Anmerkungen: |
Date Revised 01.05.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1007/s43465-021-00386-6 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM322360560 |
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| 500 | |a Date Revised 01.05.2022 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © Indian Orthopaedics Association 2021. | ||
| 520 | |a PURPOSE: Hip fractures in the elderly require a multi-disciplinary approach and are associated with increased morbidity and mortality. The current COVID-19 pandemic has affected substantially this high-risk population group. This present review was done to ascertain whether or not the pandemic has affected the 30-day mortality and outcomes of hip fracture in the elderly | ||
| 520 | |a RESEARCH QUESTION: Does the coexistence of COVID-19 infection and hip fractures in the elderly increase the mortality rates? | ||
| 520 | |a METHODOLOGY: A systematic review and meta-analysis were conducted using three databases (PubMed, EMBASE and SCOPUS) to compare the mortality rates between COVID-19 positive/suspect and COVID-19 negative patients. The secondary outcomes included comparison of in-hospital mortality, complication rate and length of hospital stay. Risk of bias assessment was done using the MINORS tool | ||
| 520 | |a RESULTS: The present review included 20 studies. Primary outcome: A significantly higher 30 day mortality rate was seen in COVID-19 positive/suspect patients with an Odds ratio of 6.09 (95% CI 4.75-8.59, p < 0.00001). Secondary outcome: We observed significantly higher rates of inpatient mortality [OR 18.22, (95% CI 7.10-46.75], complication rate (OR 9.28, 95% CI 4.46-19.30), and length of hospital stay (MD: 4.96, 95% CI 2.86-7.05) in COVID-19 positive/suspect patients as compared to COVID-19 negative patients | ||
| 520 | |a CONCLUSION: COVID-19 has deteriorated the outcomes in elderly patients with hip fractures and associated with higher rates of mortality in the short term. A multidisciplinary approach is needed to contain this "pandemic within a pandemic" and improve the overall outcome to survival | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a 30 day mortality | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Elderly | |
| 650 | 4 | |a Hip fractures | |
| 650 | 4 | |a Novel corona virus | |
| 650 | 4 | |a Proximal femur fractures | |
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| 700 | 1 | |a Aggarwal, Sameer |e verfasserin |4 aut | |
| 700 | 1 | |a Kumar, Vishal |e verfasserin |4 aut | |
| 700 | 1 | |a Rajnish, Rajesh Kumar |e verfasserin |4 aut | |
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