Usefulness of Estimated Pulse Wave Velocity in Prediction of Cardiovascular Mortality in Patients With Acute Myocardial Infarction
Copyright © 2020 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved..
BACKGROUND: Pulse wave velocity (PWV) is an excellent index of arterial stiffness and can be used to predict long-term cardiovascular (CV) outcome. In recent years, estimated PWV (ePWV), calculated by equations using age and mean blood pressure, was also reported to be a significant predictor of CV outcomes. However, there was no literature discussing about usefulness of ePWV in patients of acute myocardial infarction (AMI) for prediction of long-term CV and overall mortality. Therefore, we conducted this study for further evaluation.
METHODS: A total of 187 patients with AMI admitted to cardiac care unit were enrolled. ePWV were calculated by the equations for each patient.
RESULTS: The median follow-up to mortality was 73 months (25th-75th percentile: 8-174 months). There were 35 and 125 patients documented as CV and overall mortality, respectively. Under univariable analysis, ePWV could independently predict long-term CV and overall mortality. However, after multivariable analysis, ePWV could only predict long-term CV mortality in AMI patients.
CONCLUSIONS: To the best of our knowledge, our study was the first to evaluate the usefulness of ePWV in AMI patients for prediction of long-term CV and overall mortality. Our study showed ePWV was not only easy to calculate by formula, but also an independent predictor for long-term CV mortality in univariable and multivariable analyses. Therefore, ePWV was a simple and useful tool to measure arterial stiffness and to predict CV mortality outcome in AMI patients without the necessity for equipment to measure PWV.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:361 |
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| Enthalten in: |
The American journal of the medical sciences - 361(2021), 4 vom: 15. Apr., Seite 479-484 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hsu, Po-Chao [VerfasserIn] |
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| Links: |
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| Themen: |
Acute myocardial infarction |
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| Anmerkungen: |
Date Completed 23.04.2021 Date Revised 23.04.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.amjms.2020.10.023 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM321954203 |
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| 245 | 1 | 0 | |a Usefulness of Estimated Pulse Wave Velocity in Prediction of Cardiovascular Mortality in Patients With Acute Myocardial Infarction |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Pulse wave velocity (PWV) is an excellent index of arterial stiffness and can be used to predict long-term cardiovascular (CV) outcome. In recent years, estimated PWV (ePWV), calculated by equations using age and mean blood pressure, was also reported to be a significant predictor of CV outcomes. However, there was no literature discussing about usefulness of ePWV in patients of acute myocardial infarction (AMI) for prediction of long-term CV and overall mortality. Therefore, we conducted this study for further evaluation | ||
| 520 | |a METHODS: A total of 187 patients with AMI admitted to cardiac care unit were enrolled. ePWV were calculated by the equations for each patient | ||
| 520 | |a RESULTS: The median follow-up to mortality was 73 months (25th-75th percentile: 8-174 months). There were 35 and 125 patients documented as CV and overall mortality, respectively. Under univariable analysis, ePWV could independently predict long-term CV and overall mortality. However, after multivariable analysis, ePWV could only predict long-term CV mortality in AMI patients | ||
| 520 | |a CONCLUSIONS: To the best of our knowledge, our study was the first to evaluate the usefulness of ePWV in AMI patients for prediction of long-term CV and overall mortality. Our study showed ePWV was not only easy to calculate by formula, but also an independent predictor for long-term CV mortality in univariable and multivariable analyses. Therefore, ePWV was a simple and useful tool to measure arterial stiffness and to predict CV mortality outcome in AMI patients without the necessity for equipment to measure PWV | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Acute myocardial infarction | |
| 650 | 4 | |a Cardiovascular | |
| 650 | 4 | |a Estimated pulse wave velocity | |
| 650 | 4 | |a Mortality | |
| 700 | 1 | |a Lee, Wen-Hsien |e verfasserin |4 aut | |
| 700 | 1 | |a Tsai, Wei-Chung |e verfasserin |4 aut | |
| 700 | 1 | |a Chi, Nai-Yu |e verfasserin |4 aut | |
| 700 | 1 | |a Chang, Ching-Tang |e verfasserin |4 aut | |
| 700 | 1 | |a Chiu, Cheng-An |e verfasserin |4 aut | |
| 700 | 1 | |a Chu, Chun-Yuan |e verfasserin |4 aut | |
| 700 | 1 | |a Lin, Tsung-Hsien |e verfasserin |4 aut | |
| 700 | 1 | |a Lai, Wen-Ter |e verfasserin |4 aut | |
| 700 | 1 | |a Sheu, Sheng-Hsiung |e verfasserin |4 aut | |
| 700 | 1 | |a Su, Ho-Ming |e verfasserin |4 aut | |
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