Efficacy and Safety of Electromyography-Guided Injection of Botulinum Toxin to Treat Retrograde Cricopharyngeus Dysfunction
© The Authors 2021..
OBJECTIVE: To report the efficacy and safety of electromyography-guided percutaneous botulinum toxin injection into the cricopharyngeus muscle in an office setting for treatment of the inability to belch and associated symptoms caused by retrograde cricopharyngeus dysfunction (R-CPD).
STUDY DESIGN: Retrospective case series of treated patients.
SETTING: Tertiary care laryngology clinic.
METHODS: A retrospective review was performed on 18 consecutive patients who were diagnosed syndromically with R-CPD. The combined diagnostic test and treatment-specifically, botulinum toxin injection into the cricopharyngeus muscle-was accomplished in an office setting by a single surgeon using electromyography guidance. Items assessed are efficacy, safety, complications, and duration of benefit.
RESULTS: All 18 patients (100%) treated in the in-office setting gained the ability to burp with improvement in the associated symptoms of R-CPD at initial follow-up. Of those who had the in-office procedure performed initially, 80% maintained the ability to burp at 6 months with relief of all the associated symptoms of R-CPD. No patients experienced permanent complications from the injection, but 7 patients experienced varying degrees of noisy breathing within 1 week after the procedure, which was managed with breathing techniques and resolved.
CONCLUSION: In a case series of 18 patients with R-CPD, all patients gained the ability to burp with improvement in the majority of their symptoms of R-CPD at the time of their initial follow-up at 1 week. None experienced severe complications, and 7 experienced transient noisy breathing, which resolved.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
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| Enthalten in: |
OTO open - 5(2021), 1 vom: 12. Jan., Seite 2473974X21989587 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wajsberg, Benjamin [VerfasserIn] |
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| Links: |
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| Themen: |
Belching |
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| Anmerkungen: |
Date Revised 20.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1177/2473974X21989587 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM321574524 |
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| 245 | 1 | 0 | |a Efficacy and Safety of Electromyography-Guided Injection of Botulinum Toxin to Treat Retrograde Cricopharyngeus Dysfunction |
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| 500 | |a Date Revised 20.04.2022 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © The Authors 2021. | ||
| 520 | |a OBJECTIVE: To report the efficacy and safety of electromyography-guided percutaneous botulinum toxin injection into the cricopharyngeus muscle in an office setting for treatment of the inability to belch and associated symptoms caused by retrograde cricopharyngeus dysfunction (R-CPD) | ||
| 520 | |a STUDY DESIGN: Retrospective case series of treated patients | ||
| 520 | |a SETTING: Tertiary care laryngology clinic | ||
| 520 | |a METHODS: A retrospective review was performed on 18 consecutive patients who were diagnosed syndromically with R-CPD. The combined diagnostic test and treatment-specifically, botulinum toxin injection into the cricopharyngeus muscle-was accomplished in an office setting by a single surgeon using electromyography guidance. Items assessed are efficacy, safety, complications, and duration of benefit | ||
| 520 | |a RESULTS: All 18 patients (100%) treated in the in-office setting gained the ability to burp with improvement in the associated symptoms of R-CPD at initial follow-up. Of those who had the in-office procedure performed initially, 80% maintained the ability to burp at 6 months with relief of all the associated symptoms of R-CPD. No patients experienced permanent complications from the injection, but 7 patients experienced varying degrees of noisy breathing within 1 week after the procedure, which was managed with breathing techniques and resolved | ||
| 520 | |a CONCLUSION: In a case series of 18 patients with R-CPD, all patients gained the ability to burp with improvement in the majority of their symptoms of R-CPD at the time of their initial follow-up at 1 week. None experienced severe complications, and 7 experienced transient noisy breathing, which resolved | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a belching | |
| 650 | 4 | |a botulinum toxin | |
| 650 | 4 | |a burping | |
| 650 | 4 | |a retrograde cricopharyngeus muscle dysfunction | |
| 700 | 1 | |a Hoesli, Rebecca C |e verfasserin |4 aut | |
| 700 | 1 | |a Wingo, Melissa L |e verfasserin |4 aut | |
| 700 | 1 | |a Bastian, Robert W |e verfasserin |4 aut | |
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