Assessing the impact of COVID-19 on the health of geriatric patients : The European GeroCovid Observational Study
Copyright © 2021. Published by Elsevier B.V..
BACKGROUND: Despite the growing evidence on COVID-19, there are still many gaps in the understanding of this disease, especially in individuals in advanced age. We describe the study protocol of GeroCovid Observational, a multi-purpose, multi-setting and multicenter initiative that aims at investigating: risk factors, clinical presentation and outcomes of individuals affected by COVID-19 in acute and residential care settings; best strategies to prevent infection in long-term care facilities; and, impact of the pandemic on neuropsychologic, functional and physical health, and on medical management in outpatients and home care patients at risk of COVID-19, with a special focus on individuals with dementia.
METHODS: GeroCovid involves individuals aged ≥60 years, at risk of or affected by COVID-19, prospectively or retrospectively observed since March 1st, 2020. Data are collected in multiple investigational sites across Italy, Spain and Norway, and recorded in a de-identified clinical e-Registry. A common framework was adapted to different care settings: acute wards, long-term care facilities, geriatric outpatient and home care, and outpatient memory clinics.
RESULTS: At September 16th, 2020, 66 investigational sites obtained their Ethical Committee approval and 1618 cases (mean age 80.6 [SD=9.0] years; 45% men) have been recorded in the e-Registry. The average inclusion rate since the study start on April 25th, 2020, is 11.2 patients/day. New cases enrollment will ended on December 31st , 2020, and the clinical follow-up will end on June 30th, 2021.
CONCLUSION: GeroCovid will explore relevant aspects of COVID-19 in adults aged ≥60 years with high-quality and comprehensive data, which will help to optimize COVID-19 prevention and management, with practical implications for ongoing and possible future pandemics.
TRIAL REGISTRATION: NCT04379440 (clinicaltrial.gov).
| Errataetall: |
CommentIn: Eur J Intern Med. 2023 Nov;117:45-49. - PMID 37778903 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:87 |
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| Enthalten in: |
European journal of internal medicine - 87(2021) vom: 28. Mai, Seite 29-35 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Trevisan, Caterina [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 11.05.2021 Date Revised 28.12.2023 published: Print-Electronic ClinicalTrials.gov: NCT04379440 CommentIn: Eur J Intern Med. 2023 Nov;117:45-49. - PMID 37778903 Citation Status MEDLINE |
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| doi: |
10.1016/j.ejim.2021.01.017 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 500 | |a CommentIn: Eur J Intern Med. 2023 Nov;117:45-49. - PMID 37778903 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021. Published by Elsevier B.V. | ||
| 520 | |a BACKGROUND: Despite the growing evidence on COVID-19, there are still many gaps in the understanding of this disease, especially in individuals in advanced age. We describe the study protocol of GeroCovid Observational, a multi-purpose, multi-setting and multicenter initiative that aims at investigating: risk factors, clinical presentation and outcomes of individuals affected by COVID-19 in acute and residential care settings; best strategies to prevent infection in long-term care facilities; and, impact of the pandemic on neuropsychologic, functional and physical health, and on medical management in outpatients and home care patients at risk of COVID-19, with a special focus on individuals with dementia | ||
| 520 | |a METHODS: GeroCovid involves individuals aged ≥60 years, at risk of or affected by COVID-19, prospectively or retrospectively observed since March 1st, 2020. Data are collected in multiple investigational sites across Italy, Spain and Norway, and recorded in a de-identified clinical e-Registry. A common framework was adapted to different care settings: acute wards, long-term care facilities, geriatric outpatient and home care, and outpatient memory clinics | ||
| 520 | |a RESULTS: At September 16th, 2020, 66 investigational sites obtained their Ethical Committee approval and 1618 cases (mean age 80.6 [SD=9.0] years; 45% men) have been recorded in the e-Registry. The average inclusion rate since the study start on April 25th, 2020, is 11.2 patients/day. New cases enrollment will ended on December 31st , 2020, and the clinical follow-up will end on June 30th, 2021 | ||
| 520 | |a CONCLUSION: GeroCovid will explore relevant aspects of COVID-19 in adults aged ≥60 years with high-quality and comprehensive data, which will help to optimize COVID-19 prevention and management, with practical implications for ongoing and possible future pandemics | ||
| 520 | |a TRIAL REGISTRATION: NCT04379440 (clinicaltrial.gov) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
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| 650 | 4 | |a Inpatients | |
| 650 | 4 | |a Nursing Homes | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Outpatients | |
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| 700 | 1 | |a Malara, Alba |e verfasserin |4 aut | |
| 700 | 1 | |a Mossello, Enrico |e verfasserin |4 aut | |
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| 700 | 1 | |a Antonelli Incalzi, Raffaele |e verfasserin |4 aut | |
| 700 | 0 | |a GeroCovid Working Group |e verfasserin |4 aut | |
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