A Retrospective Analysis of the Impact of Bariatric Surgery on the Management of Chronic Migraine

PURPOSE: To investigate the association of the two most common bariatric surgical procedures, vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB), with sustained remission from chronic migraine.

MATERIALS AND METHODS: Using IBM MarketScan® research database to examine inpatient and pharmacy claims from 2010 through 2017. A cohort of bariatric patients with chronic migraine was created using inclusion and exclusion criteria. Remission was defined as no refill of first-line migraine medication for 180 days after a patients' medication was expected to run out, and recurrence as medication refill after at least 180 days of remission.

RESULTS: Of 1680 patients in our cohort, 931 (55.4%) experienced remission of migraine. Of these, 462 (49.6%) had undergone VSG, while 469 (50.4%) had undergone RYGB. Patients who underwent RYGB had an 11% (RR = 1.11, 95% CI: 1.05, 1.17) increase in likelihood of remission of migraine and a 20% (RR = 0.80, 95% CI: 0.63, 1.04) decrease in likelihood of recurrence of migraine compared to patients who underwent VSG. Older age group, higher number of medications at time of surgery, and female sex were associated with a decreased likelihood of remission.

CONCLUSION: Type of bariatric procedure, age, number of medications at surgery, and sex were the most important predictors of migraine remission after surgery.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:31

Enthalten in:

Obesity surgery - 31(2021), 5 vom: 10. Mai, Seite 2040-2049

Sprache:

Englisch

Beteiligte Personen:

Nudotor, Richard [VerfasserIn]
Yusuf, Hasiya [VerfasserIn]
Lasisi, Owulatobi [VerfasserIn]
Salia, Emmanuella [VerfasserIn]
Khalifa, Banda [VerfasserIn]
Abbey, Enoch [VerfasserIn]
Oduwole, Modupe [VerfasserIn]
Ayeh, Samuel [VerfasserIn]
Appiafo, Obeng [VerfasserIn]
Canner, Joseph [VerfasserIn]
Scheimann, Ann [VerfasserIn]
Steele, Kimberley E [VerfasserIn]

Links:

Volltext

Themen:

Bariatric surgery
Chronic migraine
Impact
Journal Article

Anmerkungen:

Date Completed 19.04.2021

Date Revised 19.04.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s11695-020-05204-w

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM321298322