Remote Continuous Glucose Monitoring With a Computerized Insulin Infusion Protocol for Critically Ill Patients in a COVID-19 Medical ICU : Proof of Concept

© 2021 by the American Diabetes Association..

OBJECTIVE: The use of remote real-time continuous glucose monitoring (CGM) in the hospital has rapidly emerged to preserve personal protective equipment and reduce potential exposures during coronavirus disease 2019 (COVID-19).

RESEARCH DESIGN AND METHODS: We linked a hybrid CGM and point-of-care (POC) glucose testing protocol to a computerized decision support system for continuous insulin infusion and integrated a validation system for sensor glucose values into the electronic health record. We report our proof-of-concept experience in a COVID-19 intensive care unit.

RESULTS: All nine patients required mechanical ventilation and corticosteroids. During the protocol, 75.7% of sensor values were within 20% of the reference POC glucose with an associated average reduction in POC of 63%. Mean time in range (70-180 mg/dL) was 71.4 ± 13.9%. Sensor accuracy was impacted by mechanical interferences in four patients.

CONCLUSIONS: A hybrid protocol integrating real-time CGM and POC is helpful for managing critically ill patients with COVID-19 requiring insulin infusion.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:44

Enthalten in:

Diabetes care - 44(2021), 4 vom: 19. Apr., Seite 1055-1058

Sprache:

Englisch

Beteiligte Personen:

Davis, Georgia M [VerfasserIn]
Faulds, Eileen [VerfasserIn]
Walker, Tara [VerfasserIn]
Vigliotti, Debbie [VerfasserIn]
Rabinovich, Marina [VerfasserIn]
Hester, Joi [VerfasserIn]
Peng, Limin [VerfasserIn]
McLean, Barbara [VerfasserIn]
Hannon, Patricia [VerfasserIn]
Poindexter, Norma [VerfasserIn]
Saunders, Petrena [VerfasserIn]
Perez-Guzman, Citlalli [VerfasserIn]
Tekwani, Seema S [VerfasserIn]
Martin, Greg S [VerfasserIn]
Umpierrez, Guillermo [VerfasserIn]
Agarwal, Shivani [VerfasserIn]
Dungan, Kathleen [VerfasserIn]
Pasquel, Francisco J [VerfasserIn]

Links:

Volltext

Themen:

Blood Glucose
Clinical Trial
Insulin
Journal Article
Research Support, N.I.H., Extramural

Anmerkungen:

Date Completed 01.04.2021

Date Revised 07.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.2337/dc20-2085

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM321238826