Acute acral eruptions in children during the COVID-19 pandemic : Characteristics of 103 children and their family clusters
Copyright © 2021. Published by Elsevier Masson SAS..
BACKGROUND: A marked increase in frequency of acute acral eruptions (AAE) was observed in children during the COVID-19 pandemic in the spring period.
OBJECTIVES: In this observational multicenter study, based on children with AAE, we aimed to assess the proportion of household members possibly infected by SARS-CoV-2.
METHODS: We collected data from all children observed with AAE, prospectively from April 7, 2020 to June 22, 2020, and retrospectively since February 28, 2020. The primary outcome was the household infection rate, defined as the proportion of family clusters having at least one member with COVID-19 infection other than the child with AAE ("index child"). The definition of a case was based on characteristic clinical signs and a positive PCR or serology.
RESULTS: The study included 103 children in 10 French departments and in Quebec. The median age was 13 years and the interquartile range [8-15], with a female-to-male ratio of 1/1.15. In children with AAE, all PCR tests were negative (n=18), and serology was positive in 2/14 (14.3%) cases. We found no significant anomalies in the lab results. A total of 66 of the 103 families (64.1%) of included children had at least one other infected member apart from the index child. The total number of household members was 292, of whom 119 (40.8%) were considered possibly infected by SARS-CoV-2. No index children or households exhibited severe COVID-19.
DISCUSSION: Among the 103 households included, 64.1% had at least one infected member. Neither children with AAE nor their households showed severe COVID-19.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:148 |
|---|---|
| Enthalten in: |
Annales de dermatologie et de venereologie - 148(2021), 2 vom: 01. Juni, Seite 94-100 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Hubiche, T [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Acral erythema |
|---|
| Anmerkungen: |
Date Completed 17.05.2021 Date Revised 16.12.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.annder.2020.11.005 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM321117379 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM321117379 | ||
| 003 | DE-627 | ||
| 005 | 20231225175130.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.annder.2020.11.005 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1070.xml |
| 035 | |a (DE-627)NLM321117379 | ||
| 035 | |a (NLM)33551211 | ||
| 035 | |a (PII)S0151-9638(21)00005-3 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Hubiche, T |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Acute acral eruptions in children during the COVID-19 pandemic |b Characteristics of 103 children and their family clusters |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 17.05.2021 | ||
| 500 | |a Date Revised 16.12.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2021. Published by Elsevier Masson SAS. | ||
| 520 | |a BACKGROUND: A marked increase in frequency of acute acral eruptions (AAE) was observed in children during the COVID-19 pandemic in the spring period | ||
| 520 | |a OBJECTIVES: In this observational multicenter study, based on children with AAE, we aimed to assess the proportion of household members possibly infected by SARS-CoV-2 | ||
| 520 | |a METHODS: We collected data from all children observed with AAE, prospectively from April 7, 2020 to June 22, 2020, and retrospectively since February 28, 2020. The primary outcome was the household infection rate, defined as the proportion of family clusters having at least one member with COVID-19 infection other than the child with AAE ("index child"). The definition of a case was based on characteristic clinical signs and a positive PCR or serology | ||
| 520 | |a RESULTS: The study included 103 children in 10 French departments and in Quebec. The median age was 13 years and the interquartile range [8-15], with a female-to-male ratio of 1/1.15. In children with AAE, all PCR tests were negative (n=18), and serology was positive in 2/14 (14.3%) cases. We found no significant anomalies in the lab results. A total of 66 of the 103 families (64.1%) of included children had at least one other infected member apart from the index child. The total number of household members was 292, of whom 119 (40.8%) were considered possibly infected by SARS-CoV-2. No index children or households exhibited severe COVID-19 | ||
| 520 | |a DISCUSSION: Among the 103 households included, 64.1% had at least one infected member. Neither children with AAE nor their households showed severe COVID-19 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Acral erythema | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Chilblains | |
| 650 | 4 | |a Children | |
| 650 | 4 | |a Familial transmission. | |
| 650 | 7 | |a Antibodies, Antinuclear |2 NLM | |
| 650 | 7 | |a Immunoglobulin G |2 NLM | |
| 700 | 1 | |a Phan, A |e verfasserin |4 aut | |
| 700 | 1 | |a Leducq, S |e verfasserin |4 aut | |
| 700 | 1 | |a Rapp, J |e verfasserin |4 aut | |
| 700 | 1 | |a Fertitta, L |e verfasserin |4 aut | |
| 700 | 1 | |a Aubert, H |e verfasserin |4 aut | |
| 700 | 1 | |a Barbarot, S |e verfasserin |4 aut | |
| 700 | 1 | |a Chiaverini, C |e verfasserin |4 aut | |
| 700 | 1 | |a Giraudeau, B |e verfasserin |4 aut | |
| 700 | 1 | |a Lasek, A |e verfasserin |4 aut | |
| 700 | 1 | |a Mallet, S |e verfasserin |4 aut | |
| 700 | 1 | |a Labarelle, A |e verfasserin |4 aut | |
| 700 | 1 | |a Piram, M |e verfasserin |4 aut | |
| 700 | 1 | |a McCuaig, C |e verfasserin |4 aut | |
| 700 | 1 | |a Martin, L |e verfasserin |4 aut | |
| 700 | 1 | |a Monitor, L |e verfasserin |4 aut | |
| 700 | 1 | |a Nicol, I |e verfasserin |4 aut | |
| 700 | 1 | |a Bissuel, M |e verfasserin |4 aut | |
| 700 | 1 | |a Bellissen, A |e verfasserin |4 aut | |
| 700 | 1 | |a Jullien, D |e verfasserin |4 aut | |
| 700 | 1 | |a Lesort, C |e verfasserin |4 aut | |
| 700 | 1 | |a Vabres, P |e verfasserin |4 aut | |
| 700 | 1 | |a Maruani, A |e verfasserin |4 aut | |
| 700 | 0 | |a Research Group of the Société Française de Dermatologie Pédiatrique (French Society of Pediatric Dermatology) |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Annales de dermatologie et de venereologie |d 1986 |g 148(2021), 2 vom: 01. Juni, Seite 94-100 |w (DE-627)NLM000154113 |x 0151-9638 |7 nnns |
| 773 | 1 | 8 | |g volume:148 |g year:2021 |g number:2 |g day:01 |g month:06 |g pages:94-100 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.annder.2020.11.005 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 148 |j 2021 |e 2 |b 01 |c 06 |h 94-100 | ||