Transcriptome-Guided Design of Physiological Multilineage Liver Organoids

Copyright © 2021. Published by Elsevier Ltd..

Despite several technical challenges, human induced pluripotent stem cell (hiPSC)-derived organoids enable biologically and clinically relevant functional study of physiology and disease. In a recent Cell Systems article, Velazquez et al. report a novel strategy to identify regulators of multilineage organoid maturation by reverse-engineering from the global transcriptome of human tissues.

Errataetall:

CommentOn: Cell Syst. 2021 Jan 20;12(1):41-55.e11. - PMID 33290741

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:37

Enthalten in:

Trends in genetics : TIG - 37(2021), 5 vom: 01. Mai, Seite 403-404

Sprache:

Englisch

Beteiligte Personen:

Zhu, Shijia [VerfasserIn]
Kubota, Naoto [VerfasserIn]
Hoshida, Yujin [VerfasserIn]

Links:

Volltext

Themen:

Comment
Gene regulatory network
Human induced pluripotent stem cell
Journal Article
Organogenesis
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 01.09.2021

Date Revised 25.07.2022

published: Print-Electronic

CommentOn: Cell Syst. 2021 Jan 20;12(1):41-55.e11. - PMID 33290741

Citation Status MEDLINE

doi:

10.1016/j.tig.2021.01.007

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM321023633