Antibodies to SARS-CoV-2 protect against re-infection during outbreaks in care homes, September and October 2020
Two London care homes experienced a second COVID-19 outbreak, with 29/209 (13.9%) SARS-CoV-2 RT-PCR-positive cases (16/103 residents, 13/106 staff). In those with prior SARS-CoV-2 exposure, 1/88 (1.1%) individuals (antibody positive: 87; RT-PCR-positive: 1) became PCR-positive compared with 22/73 (30.1%) with confirmed seronegative status. After four months protection offered by prior infection against re-infection was 96.2% (95% confidence interval (CI): 72.7-99.5%) using risk ratios from comparison of proportions and 96.1% (95% CI: 78.8-99.3%) using a penalised logistic regression model.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 26(2021), 5 vom: 04. Feb. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jeffery-Smith, Anna [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 09.02.2021 Date Revised 30.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.2807/1560-7917.ES.2021.26.5.2100092 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Two London care homes experienced a second COVID-19 outbreak, with 29/209 (13.9%) SARS-CoV-2 RT-PCR-positive cases (16/103 residents, 13/106 staff). In those with prior SARS-CoV-2 exposure, 1/88 (1.1%) individuals (antibody positive: 87; RT-PCR-positive: 1) became PCR-positive compared with 22/73 (30.1%) with confirmed seronegative status. After four months protection offered by prior infection against re-infection was 96.2% (95% confidence interval (CI): 72.7-99.5%) using risk ratios from comparison of proportions and 96.1% (95% CI: 78.8-99.3%) using a penalised logistic regression model | ||
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| 700 | 1 | |a Aiano, Felicity |e verfasserin |4 aut | |
| 700 | 1 | |a Hoschler, Katja |e verfasserin |4 aut | |
| 700 | 1 | |a Lackenby, Angie |e verfasserin |4 aut | |
| 700 | 1 | |a Ellis, Joanna |e verfasserin |4 aut | |
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| 700 | 1 | |a Amirthalingam, Gayatri |e verfasserin |4 aut | |
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| 700 | 1 | |a Zambon, Maria |e verfasserin |4 aut | |
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