Graphite-like carbon nitride-laden gold nanoparticles as signal amplification label for highly sensitive lateral flow immunoassay of 17β-estradiol
Copyright © 2021 Elsevier Ltd. All rights reserved..
Conventional gold nanoparticles-based lateral flow immunoassays (AuNPs-LFIA) lack sensitivity. In this work, we developed a graphite-like carbon nitride-laden AuNPs (g-C3N4Au) assisted LFIA to improve sensitivity for 17β-estradiol (E2) in foods. g-C3N4 nanosheets were applied as carriers, because of their excellent chemical stability, large surface areas and low-cost, loading large numbers of AuNPs to amplify signals and improve the overall response of g-C3N4@Au-based LFIA (g-C3N4@Au-LFIA). The lowest visual limit of detection (vLOD) of E2 is 0.5 ng mL-1 for g-C3N4@Au-LFIA, which exhibit a significantly three-fold improved analytical performance compared with that of AuNPs-LFIA. Additionally, this method was successfully used to the detection of E2 in four spiked food samples, offering a great potential of the g-C3N4@Au based LFIA for its application in food products.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:347 |
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| Enthalten in: |
Food chemistry - 347(2021) vom: 15. Juni, Seite 129001 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yao, Xiaolin [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 04.03.2021 Date Revised 04.03.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.foodchem.2021.129001 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Conventional gold nanoparticles-based lateral flow immunoassays (AuNPs-LFIA) lack sensitivity. In this work, we developed a graphite-like carbon nitride-laden AuNPs (g-C3N4Au) assisted LFIA to improve sensitivity for 17β-estradiol (E2) in foods. g-C3N4 nanosheets were applied as carriers, because of their excellent chemical stability, large surface areas and low-cost, loading large numbers of AuNPs to amplify signals and improve the overall response of g-C3N4@Au-based LFIA (g-C3N4@Au-LFIA). The lowest visual limit of detection (vLOD) of E2 is 0.5 ng mL-1 for g-C3N4@Au-LFIA, which exhibit a significantly three-fold improved analytical performance compared with that of AuNPs-LFIA. Additionally, this method was successfully used to the detection of E2 in four spiked food samples, offering a great potential of the g-C3N4@Au based LFIA for its application in food products | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a Food samples | |
| 650 | 4 | |a Gold nanoparticles | |
| 650 | 4 | |a Graphite-like carbon nitride | |
| 650 | 4 | |a Lateral flow immunoassay | |
| 650 | 4 | |a Signal amplification | |
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| 650 | 7 | |a graphitic carbon nitride |2 NLM | |
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| 700 | 1 | |a Zhao, Man |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Sijie |e verfasserin |4 aut | |
| 700 | 1 | |a Su, Lihong |e verfasserin |4 aut | |
| 700 | 1 | |a Dou, Leina |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Tao |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Jianlong |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Daohong |e verfasserin |4 aut | |
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