Lesson of the month : Severe granulomatosis with polyangiitis (GPA): a diagnostic challenge during the COVID-19 pandemic
© Royal College of Physicians 2021. All rights reserved..
We present the case of a 71-year-old woman with bilateral pneumonia who continued to deteriorate despite multiple courses of antibiotics. When dexamethasone was added to cover the possibility of COVID-19 pneumonia, she rapidly improved. Subsequently, she was found to have a strongly positive PR3 anti-nuclear cytoplasmic antibody (ANCA) and clinical features consistent with granulomatosis with polyangiitis (GPA) with upper respiratory tract and renal involvement. The case highlights how the COVID-19 pandemic can create new challenges in the diagnosis of GPA.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
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| Enthalten in: |
Clinical medicine (London, England) - 21(2021), 1 vom: 20. Jan., Seite 79-80 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Qurratulain, Qurratulain [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-nuclear cytoplasmic antibodies (ANCA) |
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| Anmerkungen: |
Date Completed 03.02.2021 Date Revised 26.04.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.7861/clinmed.2020-0793 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM320413489 |
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| 500 | |a Date Revised 26.04.2024 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Royal College of Physicians 2021. All rights reserved. | ||
| 520 | |a We present the case of a 71-year-old woman with bilateral pneumonia who continued to deteriorate despite multiple courses of antibiotics. When dexamethasone was added to cover the possibility of COVID-19 pneumonia, she rapidly improved. Subsequently, she was found to have a strongly positive PR3 anti-nuclear cytoplasmic antibody (ANCA) and clinical features consistent with granulomatosis with polyangiitis (GPA) with upper respiratory tract and renal involvement. The case highlights how the COVID-19 pandemic can create new challenges in the diagnosis of GPA | ||
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