Early prone positioning therapy for patients with mild COVID-19 disease
Copyright © 2020 Elsevier España, S.L.U. All rights reserved..
OBJECTIVE: In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance.
METHODS: This was a retrospective observational study. We defined the early PP group as mild COVID-19 patients who were placed into a prone position within 24h of admission; others served as the control group. We recorded basic data and outcomes of early PP and compared the results to those of controls.
RESULTS: After 1 day of treatment, oxygenation was greater in the early PP group than in the control group (P/F: 421.6±39.74 vs. 382.1±38.84mmHg [1mmHg=0.133kPa], p<0.01). And early PP group spent less total time in prone position (11.1±4.17 vs. 16.9±5.20 days, p<0.01), and required shorter hospitalization duration (12.2±4.49 vs. 23.2±4.83 days, p<0.001).
CONCLUSIONS: Early PP treatment can improve hypoxia and shorten the prone position time and hospitalization duration in mild COVID-19 patients. It is a potential clinically applicable intervention.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:156 |
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| Enthalten in: |
Medicina clinica - 156(2021), 8 vom: 23. Apr., Seite 386-389 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Liu, Xiaoyi [VerfasserIn] |
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| Links: |
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| Themen: |
ARDS |
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| Anmerkungen: |
Date Completed 20.04.2021 Date Revised 20.04.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.medcli.2020.11.036 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM320410846 |
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| 500 | |a Date Revised 20.04.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a OBJECTIVE: In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance | ||
| 520 | |a METHODS: This was a retrospective observational study. We defined the early PP group as mild COVID-19 patients who were placed into a prone position within 24h of admission; others served as the control group. We recorded basic data and outcomes of early PP and compared the results to those of controls | ||
| 520 | |a RESULTS: After 1 day of treatment, oxygenation was greater in the early PP group than in the control group (P/F: 421.6±39.74 vs. 382.1±38.84mmHg [1mmHg=0.133kPa], p<0.01). And early PP group spent less total time in prone position (11.1±4.17 vs. 16.9±5.20 days, p<0.01), and required shorter hospitalization duration (12.2±4.49 vs. 23.2±4.83 days, p<0.001) | ||
| 520 | |a CONCLUSIONS: Early PP treatment can improve hypoxia and shorten the prone position time and hospitalization duration in mild COVID-19 patients. It is a potential clinically applicable intervention | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a ARDS | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Hipoxemia | |
| 650 | 4 | |a Hypoxemia | |
| 650 | 4 | |a Posición en decúbito prono | |
| 650 | 4 | |a Prone position | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a SDRA | |
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| 700 | 1 | |a Lan, Qing |e verfasserin |4 aut | |
| 700 | 1 | |a Zheng, Xiangde |e verfasserin |4 aut | |
| 700 | 1 | |a Duan, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Zeng, Fanwei |e verfasserin |4 aut | |
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