Implications of the COVID-19 pandemic in eliminating trachoma as a public health problem
© World Health Organization, 2021. All rights reserved. The World Health Organization has granted the Publisher permission for the reproduction of this article..
BACKGROUND: Progress towards elimination of trachoma as a public health problem has been substantial, but the coronavirus disease 2019 (COVID-19) pandemic has disrupted community-based control efforts.
METHODS: We use a susceptible-infected model to estimate the impact of delayed distribution of azithromycin treatment on the prevalence of active trachoma.
RESULTS: We identify three distinct scenarios for geographic districts depending on whether the basic reproduction number and the treatment-associated reproduction number are above or below a value of 1. We find that when the basic reproduction number is <1, no significant delays in disease control will be caused. However, when the basic reproduction number is >1, significant delays can occur. In most districts, 1 y of COVID-related delay can be mitigated by a single extra round of mass drug administration. However, supercritical districts require a new paradigm of infection control because the current strategies will not eliminate disease.
CONCLUSIONS: If the pandemic can motivate judicious, community-specific implementation of control strategies, global elimination of trachoma as a public health problem could be accelerated.
| Errataetall: | |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:115 |
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| Enthalten in: |
Transactions of the Royal Society of Tropical Medicine and Hygiene - 115(2021), 3 vom: 06. März, Seite 222-228 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Blumberg, Seth [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 18.03.2021 Date Revised 26.07.2022 published: Print UpdateOf: medRxiv. 2020 Oct 27;:. - PMID 33140063 Citation Status MEDLINE |
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| doi: |
10.1093/trstmh/traa170 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM320123154 |
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| 245 | 1 | 0 | |a Implications of the COVID-19 pandemic in eliminating trachoma as a public health problem |
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| 500 | |a Date Revised 26.07.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a UpdateOf: medRxiv. 2020 Oct 27;:. - PMID 33140063 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © World Health Organization, 2021. All rights reserved. The World Health Organization has granted the Publisher permission for the reproduction of this article. | ||
| 520 | |a BACKGROUND: Progress towards elimination of trachoma as a public health problem has been substantial, but the coronavirus disease 2019 (COVID-19) pandemic has disrupted community-based control efforts | ||
| 520 | |a METHODS: We use a susceptible-infected model to estimate the impact of delayed distribution of azithromycin treatment on the prevalence of active trachoma | ||
| 520 | |a RESULTS: We identify three distinct scenarios for geographic districts depending on whether the basic reproduction number and the treatment-associated reproduction number are above or below a value of 1. We find that when the basic reproduction number is <1, no significant delays in disease control will be caused. However, when the basic reproduction number is >1, significant delays can occur. In most districts, 1 y of COVID-related delay can be mitigated by a single extra round of mass drug administration. However, supercritical districts require a new paradigm of infection control because the current strategies will not eliminate disease | ||
| 520 | |a CONCLUSIONS: If the pandemic can motivate judicious, community-specific implementation of control strategies, global elimination of trachoma as a public health problem could be accelerated | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a control | |
| 650 | 4 | |a elimination | |
| 650 | 4 | |a mass drug administration | |
| 650 | 4 | |a mathematical modelling | |
| 650 | 4 | |a trachoma | |
| 650 | 7 | |a Anti-Bacterial Agents |2 NLM | |
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| 700 | 1 | |a Borlase, Anna |e verfasserin |4 aut | |
| 700 | 1 | |a Prada, Joaquin M |e verfasserin |4 aut | |
| 700 | 1 | |a Solomon, Anthony W |e verfasserin |4 aut | |
| 700 | 1 | |a Emerson, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Hooper, Pamela J |e verfasserin |4 aut | |
| 700 | 1 | |a Deiner, Michael S |e verfasserin |4 aut | |
| 700 | 1 | |a Amoah, Benjamin |e verfasserin |4 aut | |
| 700 | 1 | |a Hollingsworth, T Déirdre |e verfasserin |4 aut | |
| 700 | 1 | |a Porco, Travis C |e verfasserin |4 aut | |
| 700 | 1 | |a Lietman, Thomas M |e verfasserin |4 aut | |
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