Predictive value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Vaginitis
Copyright: © Pakistan Journal of Medical Sciences..
OBJECTIVES: This study was conducted to evaluate the diagnostic value of platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in vaginitis patients.
METHODS: This cross-sectional retrospective study was performed in Afyon Dinar State Hospital between July 2016 to August 2017. A total of 64 bacterial vaginosis (BV) patients, 66 vulvovaginal candidiasis (VVC) patients and 65 age-matched control subjects were enrolled. NLR, PLR, mean platelet volume (MPV), red cell distribution width (RDW) and other conventional inflammatory marker values were recorded for all patients before and after treatment.
RESULTS: In the BV group, NLR values were found to be elevated compared to VVC and healthy controls [2.9 (1.2-14.7), 2.1 (1.1-11.7) and 2.1 (0.8-7.0), respectively] (p=0.008). Although not found to be statistically significant, the median NLR levels of BV patients decreased from 2.9 (1.2-14.7) to 2.4 (1.2-7.0) after treatment. PLR levels did not show a statistically significant difference between the three groups (p=0.970). The cut-off value of the NLR for BV was 2.19, with 67.2% sensitivity and 63.8% specificity.
CONCLUSIONS: The present study demonstrated that NLR levels are elevated in bacterial vaginosis and NLR levels can be used as a reflection of systemic inflammatory response in vaginosis patients.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:37 |
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Enthalten in: |
Pakistan journal of medical sciences - 37(2021), 1 vom: 25. Jan., Seite 250-255 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Pek, Eren [VerfasserIn] |
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Links: |
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Themen: |
Bacterial vaginosis |
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Anmerkungen: |
Date Revised 19.04.2022 published: Print Citation Status PubMed-not-MEDLINE |
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doi: |
10.12669/pjms.37.1.2774 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM320006328 |
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500 | |a Citation Status PubMed-not-MEDLINE | ||
520 | |a Copyright: © Pakistan Journal of Medical Sciences. | ||
520 | |a OBJECTIVES: This study was conducted to evaluate the diagnostic value of platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in vaginitis patients | ||
520 | |a METHODS: This cross-sectional retrospective study was performed in Afyon Dinar State Hospital between July 2016 to August 2017. A total of 64 bacterial vaginosis (BV) patients, 66 vulvovaginal candidiasis (VVC) patients and 65 age-matched control subjects were enrolled. NLR, PLR, mean platelet volume (MPV), red cell distribution width (RDW) and other conventional inflammatory marker values were recorded for all patients before and after treatment | ||
520 | |a RESULTS: In the BV group, NLR values were found to be elevated compared to VVC and healthy controls [2.9 (1.2-14.7), 2.1 (1.1-11.7) and 2.1 (0.8-7.0), respectively] (p=0.008). Although not found to be statistically significant, the median NLR levels of BV patients decreased from 2.9 (1.2-14.7) to 2.4 (1.2-7.0) after treatment. PLR levels did not show a statistically significant difference between the three groups (p=0.970). The cut-off value of the NLR for BV was 2.19, with 67.2% sensitivity and 63.8% specificity | ||
520 | |a CONCLUSIONS: The present study demonstrated that NLR levels are elevated in bacterial vaginosis and NLR levels can be used as a reflection of systemic inflammatory response in vaginosis patients | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Bacterial vaginosis | |
650 | 4 | |a Mean platelet volume | |
650 | 4 | |a Neutrophil-lymphocyte ratio | |
650 | 4 | |a Platelet-lymphocyte ratio | |
650 | 4 | |a Vulvovaginal candidiasis | |
700 | 1 | |a Beyazit, Fatma |e verfasserin |4 aut | |
700 | 1 | |a Korkmaz, Nilay Sen |e verfasserin |4 aut | |
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