Incidence and age-standardized rates of pancreatic cancer in Sri Lanka from 2001 to 2010 : An analysis of national cancer registry data
BACKGROUND: Varying trends in the incidence of pancreatic cancer (PC) are observed in many Asian countries. This study aimed at describing the incidence and age-standardized rates of PC in Sri Lanka from 2001-2010.
METHODS: A retrospective cohort evaluation of patients with PC from 2001 to 2010 was performed using the population-based data published by the Sri Lanka National Cancer Registry. The trends in the incidence of PC was analyzed by age and sex using joinpoint regression analysis.
RESULTS: A total of 808 PC patients studied from 2001-2010, of which males were 438 (54.2%). The mean (±standard deviation) age of the total population was 55.7 (±13.8) years [males = 56.5 (±13.3) vs. females = 54.8 (±14.3), P=0.07]. The World Health Organization (WHO) age-standardized incidence of PC in Sri Lanka increased marginally from 0.44 per 100,000 in 2001 (95% confidence interval (CI) = 0.34-0.54) to 0.58 per 100,000 in 2010 (95% CI = 0.46-0.69) which is a 1.3-fold increase (P < 0.05 for trend) with an estimated annual percentage change (EAPC) of 3.5 (95% CI = 0.5-6.6). The proportional increase in incidence was more significant in females compared to males. The analysis of the overall cohort rates of PC in Srilanka between 2001-2010 showed the highest rates in the 60-70-year category with an EAPC of 5.06 (95% CI = 1.3-9.0).
CONCLUSION: In our study, we found that there was a marginal rise in the incidence of PC in Sri Lanka with a higher proportional increase in females compared to males.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:58 |
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| Enthalten in: |
Indian journal of cancer - 58(2021), 3 vom: 02. Juli, Seite 387-393 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jayarajah, Umesh [VerfasserIn] |
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| Links: |
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| Themen: |
Age-standardized rate |
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| Anmerkungen: |
Date Completed 04.01.2022 Date Revised 13.12.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.4103/ijc.IJC_238_19 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM319663833 |
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| 100 | 1 | |a Jayarajah, Umesh |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Incidence and age-standardized rates of pancreatic cancer in Sri Lanka from 2001 to 2010 |b An analysis of national cancer registry data |
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| 500 | |a Date Completed 04.01.2022 | ||
| 500 | |a Date Revised 13.12.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Varying trends in the incidence of pancreatic cancer (PC) are observed in many Asian countries. This study aimed at describing the incidence and age-standardized rates of PC in Sri Lanka from 2001-2010 | ||
| 520 | |a METHODS: A retrospective cohort evaluation of patients with PC from 2001 to 2010 was performed using the population-based data published by the Sri Lanka National Cancer Registry. The trends in the incidence of PC was analyzed by age and sex using joinpoint regression analysis | ||
| 520 | |a RESULTS: A total of 808 PC patients studied from 2001-2010, of which males were 438 (54.2%). The mean (±standard deviation) age of the total population was 55.7 (±13.8) years [males = 56.5 (±13.3) vs. females = 54.8 (±14.3), P=0.07]. The World Health Organization (WHO) age-standardized incidence of PC in Sri Lanka increased marginally from 0.44 per 100,000 in 2001 (95% confidence interval (CI) = 0.34-0.54) to 0.58 per 100,000 in 2010 (95% CI = 0.46-0.69) which is a 1.3-fold increase (P < 0.05 for trend) with an estimated annual percentage change (EAPC) of 3.5 (95% CI = 0.5-6.6). The proportional increase in incidence was more significant in females compared to males. The analysis of the overall cohort rates of PC in Srilanka between 2001-2010 showed the highest rates in the 60-70-year category with an EAPC of 5.06 (95% CI = 1.3-9.0) | ||
| 520 | |a CONCLUSION: In our study, we found that there was a marginal rise in the incidence of PC in Sri Lanka with a higher proportional increase in females compared to males | ||
| 650 | 4 | |a Historical Article | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Age-standardized rate | |
| 650 | 4 | |a Sri Lanka | |
| 650 | 4 | |a incidence | |
| 650 | 4 | |a national cancer registry | |
| 650 | 4 | |a pancreatic cancer | |
| 650 | 4 | |a pancreatic neoplasms | |
| 700 | 1 | |a Almeida, Isuru |e verfasserin |4 aut | |
| 700 | 1 | |a Fernando, Ashan |e verfasserin |4 aut | |
| 700 | 1 | |a Seneviratne, Sanjeewa |e verfasserin |4 aut | |
| 700 | 1 | |a Samarasekera, Dharmabandhu Nandadeva |e verfasserin |4 aut | |
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