Spacer microbial contamination and asthma outcomes : case series
OBJECTIVE: The primary method of drug delivery to treat asthma is through pressurized metered dose inhalers (pMDI). Asthma guidelines recommend that providers prescribe a spacer for all patients using pMDI. The objective of this study was to examine whether microbial contamination of spacer devices is associated with poor asthma outcomes.
METHODS: This was a cross-sectional, single-center case series of seven pediatric patients with persistent asthma who had previously been prescribed a spacer. Spacers were swabbed with sterile cotton and samples assessed for bacterial/fungal growth. Parents completed a questionnaire including Asthma Control Test (ACT) and asthma control was assessed by an Allergist/Immunologist physician.
RESULTS: Two (n = 2) children's parent-completed ACT score indicated poorly controlled asthma and three (n = 3) patients were noted to be poorly controlled by the physician. All but one caregiver reported cleaning the spacer with most reporting (n = 5) that they cleaned their child's spacer monthly and one (n = 1) reporting cleaning it every two weeks. One spacer had detected Candida albicans. There was not a statistically significant association between ACT score and microbial growth (p > 0.05).
CONCLUSION: Most spacers in a pediatric sample were not contaminated, despite lack of consistent cleaning, as recommended by spacer manufacturers. Providers and pharmacists should discuss proper cleaning of spacers with caregivers of pediatric patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:59 |
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| Enthalten in: |
The Journal of asthma : official journal of the Association for the Care of Asthma - 59(2022), 4 vom: 28. Apr., Seite 755-756 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shepherd, Meagan W [VerfasserIn] |
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| Links: |
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| Themen: |
Aerochamber |
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| Anmerkungen: |
Date Completed 11.04.2022 Date Revised 07.07.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/02770903.2020.1870128 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM319443116 |
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| 100 | 1 | |a Shepherd, Meagan W |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Spacer microbial contamination and asthma outcomes |b case series |
| 264 | 1 | |c 2022 | |
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| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
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| 500 | |a Date Completed 11.04.2022 | ||
| 500 | |a Date Revised 07.07.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: The primary method of drug delivery to treat asthma is through pressurized metered dose inhalers (pMDI). Asthma guidelines recommend that providers prescribe a spacer for all patients using pMDI. The objective of this study was to examine whether microbial contamination of spacer devices is associated with poor asthma outcomes | ||
| 520 | |a METHODS: This was a cross-sectional, single-center case series of seven pediatric patients with persistent asthma who had previously been prescribed a spacer. Spacers were swabbed with sterile cotton and samples assessed for bacterial/fungal growth. Parents completed a questionnaire including Asthma Control Test (ACT) and asthma control was assessed by an Allergist/Immunologist physician | ||
| 520 | |a RESULTS: Two (n = 2) children's parent-completed ACT score indicated poorly controlled asthma and three (n = 3) patients were noted to be poorly controlled by the physician. All but one caregiver reported cleaning the spacer with most reporting (n = 5) that they cleaned their child's spacer monthly and one (n = 1) reporting cleaning it every two weeks. One spacer had detected Candida albicans. There was not a statistically significant association between ACT score and microbial growth (p > 0.05) | ||
| 520 | |a CONCLUSION: Most spacers in a pediatric sample were not contaminated, despite lack of consistent cleaning, as recommended by spacer manufacturers. Providers and pharmacists should discuss proper cleaning of spacers with caregivers of pediatric patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Spacer | |
| 650 | 4 | |a aerochamber | |
| 650 | 4 | |a asthma control | |
| 650 | 4 | |a contamination | |
| 650 | 4 | |a device | |
| 650 | 4 | |a facemask | |
| 700 | 1 | |a Hogan, Mary Beth |e verfasserin |4 aut | |
| 700 | 1 | |a Hayes, Rebecca |e verfasserin |4 aut | |
| 700 | 1 | |a Flesher, Susan |e verfasserin |4 aut | |
| 700 | 1 | |a Gillette, Chris |e verfasserin |4 aut | |
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