TfOH-Catalyzed N-H Insertion of α-Substituted-α-Diazoesters with Anilines Provides Access to Unnatural α-Amino Esters
A time-economical TfOH-catalyzed N-H insertion between anilines and α-alkyl and α-aryl-α-diazoacetates provides a straightforward approach to access unnatural α-amino esters, which readily undergo various transformations and can thus be used for the synthesis of pharmaceutically relevant molecules. The α-amino esters were obtained in moderate to excellent yields.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:86 |
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| Enthalten in: |
The Journal of organic chemistry - 86(2021), 4 vom: 19. Feb., Seite 3223-3231 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hu, Sha [VerfasserIn] |
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| Links: |
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| Themen: |
Aniline Compounds |
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| Anmerkungen: |
Date Completed 02.07.2021 Date Revised 02.07.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1021/acs.joc.0c02588 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM31942300X |
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| 245 | 1 | 0 | |a TfOH-Catalyzed N-H Insertion of α-Substituted-α-Diazoesters with Anilines Provides Access to Unnatural α-Amino Esters |
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| 500 | |a Date Revised 02.07.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A time-economical TfOH-catalyzed N-H insertion between anilines and α-alkyl and α-aryl-α-diazoacetates provides a straightforward approach to access unnatural α-amino esters, which readily undergo various transformations and can thus be used for the synthesis of pharmaceutically relevant molecules. The α-amino esters were obtained in moderate to excellent yields | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Aniline Compounds |2 NLM | |
| 650 | 7 | |a Esters |2 NLM | |
| 700 | 1 | |a Wu, Jiale |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, Zuolin |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Jiaqi |e verfasserin |4 aut | |
| 700 | 1 | |a Tao, Yuan |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Meifen |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Fener |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The Journal of organic chemistry |d 1945 |g 86(2021), 4 vom: 19. Feb., Seite 3223-3231 |w (DE-627)NLM000006343 |x 1520-6904 |7 nnns |
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