Serum albumin measurement in nephrology : room for improvement
© The Author(s) 2020. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved..
Serum albumin is a widely used biomarker in clinical nephrology. Serum albumin cut-off values are used to define disease, to predict outcome and to guide patient care. The available commercial assays to measure serum albumin rely on different analytical principles, all with their own (analytical) specifications. This article provides an overview of the different clinical applications of serum albumin measurements in nephrology, the (dis)advantages of the available assays and the estimates of the effects of the measurement uncertainty between different assays in clinical decision making. This article concludes that harmonization of serum albumin assay results is needed.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:37 |
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Enthalten in: |
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 37(2022), 10 vom: 22. Sept., Seite 1792-1799 |
Sprache: |
Englisch |
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Beteiligte Personen: |
van Schrojenstein Lantman, Marith [VerfasserIn] |
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Links: |
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Themen: |
Clinical decision making |
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Anmerkungen: |
Date Completed 23.09.2022 Date Revised 26.10.2022 published: Print Citation Status MEDLINE |
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doi: |
10.1093/ndt/gfaa375 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM319321827 |
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520 | |a Serum albumin is a widely used biomarker in clinical nephrology. Serum albumin cut-off values are used to define disease, to predict outcome and to guide patient care. The available commercial assays to measure serum albumin rely on different analytical principles, all with their own (analytical) specifications. This article provides an overview of the different clinical applications of serum albumin measurements in nephrology, the (dis)advantages of the available assays and the estimates of the effects of the measurement uncertainty between different assays in clinical decision making. This article concludes that harmonization of serum albumin assay results is needed | ||
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