Bee sting envenomation severe cases in Manaus, Brazilian Amazon : clinical characteristics and immune markers of case reports
Bee venom is a natural toxin composed of several peptides. Massive envenoming causes severe local and systemic reactions. We report two cases of severe bee envenomation, of which one was fatal. We also describe clinical characteristics and immune markers. Both victims suffered from respiratory distress, renal failure, rhabdomyolysis, and shock. They required invasive mechanical ventilation, vasoactive drugs, and renal replacement therapy. Moreover, serum levels of chemokines, cytokines, and cell-free circulating nucleic acids demonstrated an intense inflammatory process. Massive envenoming produced systemic injury in the victims, with an uncontrolled inflammatory response, and a more significant chemotactic response in the fatal case.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:54 |
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| Enthalten in: |
Revista da Sociedade Brasileira de Medicina Tropical - 54(2020) vom: 21., Seite e20200319 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Mendonça-da-Silva, Iran [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 22.12.2020 Date Revised 23.12.2020 published: Electronic-eCollection Citation Status MEDLINE |
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| doi: |
10.1590/0037-8682-0319-2021 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM319030369 |
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| 520 | |a Bee venom is a natural toxin composed of several peptides. Massive envenoming causes severe local and systemic reactions. We report two cases of severe bee envenomation, of which one was fatal. We also describe clinical characteristics and immune markers. Both victims suffered from respiratory distress, renal failure, rhabdomyolysis, and shock. They required invasive mechanical ventilation, vasoactive drugs, and renal replacement therapy. Moreover, serum levels of chemokines, cytokines, and cell-free circulating nucleic acids demonstrated an intense inflammatory process. Massive envenoming produced systemic injury in the victims, with an uncontrolled inflammatory response, and a more significant chemotactic response in the fatal case | ||
| 650 | 4 | |a Case Reports | |
| 650 | 7 | |a Bee Venoms |2 NLM | |
| 650 | 7 | |a Biomarkers |2 NLM | |
| 700 | 1 | |a Monteiro, Wuelton Marcelo |e verfasserin |4 aut | |
| 700 | 1 | |a Sachett, Jacqueline Almeida Gonçalves |e verfasserin |4 aut | |
| 700 | 1 | |a Barbosa, Endila Souza |e verfasserin |4 aut | |
| 700 | 1 | |a Cordeiro-Dos-Santos, Marcelo |e verfasserin |4 aut | |
| 700 | 1 | |a Lacerda, Marcus Vinícius Guimarães |e verfasserin |4 aut | |
| 700 | 1 | |a Melo, Gisely Cardoso |e verfasserin |4 aut | |
| 700 | 1 | |a Costa, Allyson Guimarães |e verfasserin |4 aut | |
| 700 | 1 | |a Val, Fernando Fonseca Almeida |e verfasserin |4 aut | |
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