Natural SARS-CoV-2 infections, including virus isolation, among serially tested cats and dogs in households with confirmed human COVID-19 cases in Texas, USA
The natural infections and epidemiological roles of household pets in SARS-CoV-2 transmission are not understood. We conducted a longitudinal study of dogs and cats living with at least one SARS-CoV-2 infected human in Texas and found 47.1% of 17 cats and 15.3% of 59 dogs from 25.6% of 39 households were positive for SARS-CoV-2 via RT-PCR and genome sequencing or neutralizing antibodies. Virus was isolated from one cat. The majority (82.4%) of infected pets were asymptomatic. Re-sampling of one infected cat showed persistence of viral RNA at least 32 d-post human diagnosis (25 d-post initial test). Across 15 antibody-positive animals, titers increased (33.3%), decreased (33.3%) or were stable (33.3%) over time. A One Health approach is informative for prevention and control of SARS-CoV-2 transmission.
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2020 |
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| Enthalten in: |
bioRxiv : the preprint server for biology - (2020) vom: 08. Dez. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hamer, Sarah A [VerfasserIn] |
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Date Revised 30.03.2024 published: Electronic UpdateIn: Viruses. 2021 May 19;13(5):. - PMID 34069453 Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1101/2020.12.08.416339 |
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| funding: |
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| PPN (Katalog-ID): |
NLM318959135 |
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| 500 | |a published: Electronic | ||
| 500 | |a UpdateIn: Viruses. 2021 May 19;13(5):. - PMID 34069453 | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a The natural infections and epidemiological roles of household pets in SARS-CoV-2 transmission are not understood. We conducted a longitudinal study of dogs and cats living with at least one SARS-CoV-2 infected human in Texas and found 47.1% of 17 cats and 15.3% of 59 dogs from 25.6% of 39 households were positive for SARS-CoV-2 via RT-PCR and genome sequencing or neutralizing antibodies. Virus was isolated from one cat. The majority (82.4%) of infected pets were asymptomatic. Re-sampling of one infected cat showed persistence of viral RNA at least 32 d-post human diagnosis (25 d-post initial test). Across 15 antibody-positive animals, titers increased (33.3%), decreased (33.3%) or were stable (33.3%) over time. A One Health approach is informative for prevention and control of SARS-CoV-2 transmission | ||
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| 700 | 1 | |a Zecca, Italo B |e verfasserin |4 aut | |
| 700 | 1 | |a Davila, Edward |e verfasserin |4 aut | |
| 700 | 1 | |a Auckland, Lisa D |e verfasserin |4 aut | |
| 700 | 1 | |a Roundy, Christopher M |e verfasserin |4 aut | |
| 700 | 1 | |a Tang, Wendy |e verfasserin |4 aut | |
| 700 | 1 | |a Torchetti, Mia |e verfasserin |4 aut | |
| 700 | 1 | |a Killian, Mary Lea |e verfasserin |4 aut | |
| 700 | 1 | |a Jenkins-Moore, Melinda |e verfasserin |4 aut | |
| 700 | 1 | |a Mozingo, Katie |e verfasserin |4 aut | |
| 700 | 1 | |a Akpalu, Yao |e verfasserin |4 aut | |
| 700 | 1 | |a Ghai, Ria R |e verfasserin |4 aut | |
| 700 | 1 | |a Spengler, Jessica R |e verfasserin |4 aut | |
| 700 | 1 | |a Behravesh, Casey Barton |e verfasserin |4 aut | |
| 700 | 1 | |a Fischer, Rebecca S B |e verfasserin |4 aut | |
| 700 | 1 | |a Hamer, Gabriel L |e verfasserin |4 aut | |
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