The Gut Microbiome as a Reservoir for Antimicrobial Resistance

© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com..

This review will consider the gut as a reservoir for antimicrobial resistance, colonization resistance, and how disruption of the microbiome can lead to colonization by pathogenic organisms. There is a focus on the gut as a reservoir for β-lactam and plasmid-mediated quinolone resistance. Finally, the role of functional metagenomics and long-read sequencing technologies to detect and understand antimicrobial resistance genes within the gut microbiome is discussed, along with the potential for future microbiome-directed methods to detect and prevent infection.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:223

Enthalten in:

The Journal of infectious diseases - 223(2021), 12 Suppl 2 vom: 16. Juni, Seite S209-S213

Sprache:

Englisch

Beteiligte Personen:

Anthony, Winston E [VerfasserIn]
Burnham, Carey-Ann D [VerfasserIn]
Dantas, Gautam [VerfasserIn]
Kwon, Jennie H [VerfasserIn]

Links:

Volltext

Themen:

Anti-Infective Agents
Antibiotic resistance
Antimicrobial resistance
Journal Article
Microbiome
Research Support, N.I.H., Extramural
Resistome
Review

Anmerkungen:

Date Completed 01.10.2021

Date Revised 02.04.2024

published: Print

Citation Status MEDLINE

doi:

10.1093/infdis/jiaa497

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM318916479