The Gut Microbiome as a Reservoir for Antimicrobial Resistance
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com..
This review will consider the gut as a reservoir for antimicrobial resistance, colonization resistance, and how disruption of the microbiome can lead to colonization by pathogenic organisms. There is a focus on the gut as a reservoir for β-lactam and plasmid-mediated quinolone resistance. Finally, the role of functional metagenomics and long-read sequencing technologies to detect and understand antimicrobial resistance genes within the gut microbiome is discussed, along with the potential for future microbiome-directed methods to detect and prevent infection.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:223 |
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Enthalten in: |
The Journal of infectious diseases - 223(2021), 12 Suppl 2 vom: 16. Juni, Seite S209-S213 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Anthony, Winston E [VerfasserIn] |
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Links: |
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Themen: |
Anti-Infective Agents |
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Anmerkungen: |
Date Completed 01.10.2021 Date Revised 02.04.2024 published: Print Citation Status MEDLINE |
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doi: |
10.1093/infdis/jiaa497 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM318916479 |
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520 | |a This review will consider the gut as a reservoir for antimicrobial resistance, colonization resistance, and how disruption of the microbiome can lead to colonization by pathogenic organisms. There is a focus on the gut as a reservoir for β-lactam and plasmid-mediated quinolone resistance. Finally, the role of functional metagenomics and long-read sequencing technologies to detect and understand antimicrobial resistance genes within the gut microbiome is discussed, along with the potential for future microbiome-directed methods to detect and prevent infection | ||
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