Unusual onset of thyroid associated orbitopathy during pregnancy : case report and review of literature
BACKGROUND: Thyroid associated orbitopathy (TAO) is the most common extrathyroidal complication of Graves' disease. The disease course ranges from mild, where symptomatic therapy is sufficient, to severe, where high dose steroid administration or orbital decompression surgery is required. Women of their reproductive age are more likely to be affected. Although pregnancy is a state of enhanced immune tolerance, TAO may develop or worsen in 0.2-0.4% of pregnant women.
CASE PRESENTATION: We present the case of a 19-year-old woman who has developed hyperthyroidism and progressive TAO during the second trimester of her third pregnancy, which has improved postpartum. The possible mechanisms and the importance of follow up in pregnancy is discussed.
CONCLUSIONS: Expectant mothers with Graves' disease require follow up of eye signs throughout pregnancy, preferably in the setting of a thyroid-eye clinic.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:20 |
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| Enthalten in: |
BMC endocrine disorders - 20(2020), 1 vom: 15. Dez., Seite 183 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Aranyosi, Janos K [VerfasserIn] |
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| Links: |
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| Themen: |
Case Reports |
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| Anmerkungen: |
Date Completed 28.09.2021 Date Revised 28.09.2021 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1186/s12902-020-00663-9 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM318827166 |
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| 245 | 1 | 0 | |a Unusual onset of thyroid associated orbitopathy during pregnancy |b case report and review of literature |
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| 500 | |a Date Revised 28.09.2021 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Thyroid associated orbitopathy (TAO) is the most common extrathyroidal complication of Graves' disease. The disease course ranges from mild, where symptomatic therapy is sufficient, to severe, where high dose steroid administration or orbital decompression surgery is required. Women of their reproductive age are more likely to be affected. Although pregnancy is a state of enhanced immune tolerance, TAO may develop or worsen in 0.2-0.4% of pregnant women | ||
| 520 | |a CASE PRESENTATION: We present the case of a 19-year-old woman who has developed hyperthyroidism and progressive TAO during the second trimester of her third pregnancy, which has improved postpartum. The possible mechanisms and the importance of follow up in pregnancy is discussed | ||
| 520 | |a CONCLUSIONS: Expectant mothers with Graves' disease require follow up of eye signs throughout pregnancy, preferably in the setting of a thyroid-eye clinic | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Case report | |
| 650 | 4 | |a Graves’ disease | |
| 650 | 4 | |a Orbitopathy | |
| 650 | 4 | |a Pregnancy | |
| 650 | 4 | |a Smoking | |
| 650 | 4 | |a TAO | |
| 650 | 7 | |a Thyroid Hormones |2 NLM | |
| 700 | 1 | |a Deli, Tamas |e verfasserin |4 aut | |
| 700 | 1 | |a Erdei, Annamaria |e verfasserin |4 aut | |
| 700 | 1 | |a Toth, Geza |e verfasserin |4 aut | |
| 700 | 1 | |a Jakab, Attila |e verfasserin |4 aut | |
| 700 | 1 | |a Fodor, Mariann |e verfasserin |4 aut | |
| 700 | 1 | |a Nagy, Endre V |e verfasserin |4 aut | |
| 700 | 1 | |a Ujhelyi, Bernadett |e verfasserin |4 aut | |
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