Cutaneous Manifestations Associated with COVID-19 : A Narrative Review
INTRODUCTION: COVID-19 is an infectious disease caused by the new coronavirus, SARS-CoV-2, that has spread rapidly throughout the world. This has resulted in an urgent need to obtain information regarding its pathogenesis, diagnosis and clinical manifestations. More specifically, skin manifestations, seldom reported initially, have been increasingly described.
MATERIAL AND METHODS: We performed a literature search in the PubMed database, regarding cutaneous manifestations associated with COVID-19. This article describes the clinical and histological findings of the main skin lesions observed in the context of SARS-CoV-2 infection.
DISCUSSION: Cutaneous manifestations associated with COVID-19 have been described in multiple retrospective and prospective studies, case series and case reports. The reported incidence reached 20.4%. Although there was substantial heterogeneity in terms of clinical patterns, the main ones include: erythematous/maculopapular, urticarial, papulovesicular, and purpuric/petechial eruptions, chilblain-like lesions and livedoid/acro-ischemic lesions. In the vast majority, the underlying pathophysiologic mechanisms are not fully understood, although histopathological findings and biomolecular studies can add relevant data.
CONCLUSION: The recognition of cutaneous manifestations associated with COVID-19 is of utmost importance. They may help establishing an early diagnosis, namely in oligosymptomatic patients or when confirmatory tests are impossible to perform. Moreover, chilblain-like lesions and acro-ischemia, also seem to play an important role in terms of prognosis.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:34 |
|---|---|
| Enthalten in: |
Acta medica portuguesa - 34(2021), 2 vom: 01. Feb., Seite 128-136 |
| Sprache: |
Portugiesisch |
|---|
| Weiterer Titel: |
Manifestações Cutâneas Associadas à COVID-19: Uma Revisão Narrativa |
|---|
| Beteiligte Personen: |
Relvas, Maria [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
COVID-19 |
|---|
| Anmerkungen: |
Date Completed 10.03.2021 Date Revised 10.03.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.20344/amp.14574 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM318802635 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM318802635 | ||
| 003 | DE-627 | ||
| 005 | 20231225170123.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||por c | ||
| 024 | 7 | |a 10.20344/amp.14574 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1062.xml |
| 035 | |a (DE-627)NLM318802635 | ||
| 035 | |a (NLM)33315008 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a por | ||
| 100 | 1 | |a Relvas, Maria |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Cutaneous Manifestations Associated with COVID-19 |b A Narrative Review |
| 246 | 3 | 3 | |a Manifestações Cutâneas Associadas à COVID-19: Uma Revisão Narrativa |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 10.03.2021 | ||
| 500 | |a Date Revised 10.03.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a INTRODUCTION: COVID-19 is an infectious disease caused by the new coronavirus, SARS-CoV-2, that has spread rapidly throughout the world. This has resulted in an urgent need to obtain information regarding its pathogenesis, diagnosis and clinical manifestations. More specifically, skin manifestations, seldom reported initially, have been increasingly described | ||
| 520 | |a MATERIAL AND METHODS: We performed a literature search in the PubMed database, regarding cutaneous manifestations associated with COVID-19. This article describes the clinical and histological findings of the main skin lesions observed in the context of SARS-CoV-2 infection | ||
| 520 | |a DISCUSSION: Cutaneous manifestations associated with COVID-19 have been described in multiple retrospective and prospective studies, case series and case reports. The reported incidence reached 20.4%. Although there was substantial heterogeneity in terms of clinical patterns, the main ones include: erythematous/maculopapular, urticarial, papulovesicular, and purpuric/petechial eruptions, chilblain-like lesions and livedoid/acro-ischemic lesions. In the vast majority, the underlying pathophysiologic mechanisms are not fully understood, although histopathological findings and biomolecular studies can add relevant data | ||
| 520 | |a CONCLUSION: The recognition of cutaneous manifestations associated with COVID-19 is of utmost importance. They may help establishing an early diagnosis, namely in oligosymptomatic patients or when confirmatory tests are impossible to perform. Moreover, chilblain-like lesions and acro-ischemia, also seem to play an important role in terms of prognosis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Coronavirus Infections | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a Skin Manifestations | |
| 700 | 1 | |a Calvão, Joana |e verfasserin |4 aut | |
| 700 | 1 | |a Oliveira, Raquel |e verfasserin |4 aut | |
| 700 | 1 | |a Cardoso, José Carlos |e verfasserin |4 aut | |
| 700 | 1 | |a Gonçalo, Margarida |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Acta medica portuguesa |d 1993 |g 34(2021), 2 vom: 01. Feb., Seite 128-136 |w (DE-627)NLM000463329 |x 1646-0758 |7 nnns |
| 773 | 1 | 8 | |g volume:34 |g year:2021 |g number:2 |g day:01 |g month:02 |g pages:128-136 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.20344/amp.14574 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 34 |j 2021 |e 2 |b 01 |c 02 |h 128-136 | ||