Impact of renal function on the prognosis of acute pulmonary embolism patients : a systematic review and meta-analysis
OBJECTIVES: We conduct a study to explore the influence of impaired renal function on prognosis in Acute pulmonary embolism (APE) patients.
METHODS: A meta-analysis was performed using the EMBASE and PubMed databases for relevant publications reporting the impact of impaired renal function on the clinical outcomes in patients with APE.
RESULTS: Eventually, 17 articles were included in our analysis. The results suggested that renal insufficiency (RI) is a predictor of poor prognosis in APE patients(short-term mortality: pooled OR = 2.83, 95%CI: 2.20-3.63; long-term mortality: pooled OR = 2.30, 95%CI: 1.72-3.08; adverse outcomes: pooled OR = 3.02, 95%CI: 2.60-3.51). The short-term and long-term mortality rates of APE patients with RI were both higher than those in patients without RI. In addition, acute kidney injury(AKI) could serve as a predictive factor of poor prognosis (pooled OR = 2.75, 95%CI: 2.45-3.08), and it doubles the overall mortality rate in APE patients. However, chronic kidney disease (CKD) did not predict poor prognosis in APE patients (pooled OR = 1.94, 95%CI: 0.99-3.81), although it could slightly increase the overall mortality rate in APE patients.
CONCLUSIONS: RI and AKI could be included in the prognosis evaluation for APE, but the impact of CKD in APE patients has yet to be determined.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
|---|---|
| Enthalten in: |
Expert review of respiratory medicine - 16(2022), 1 vom: 05. Jan., Seite 91-98 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Xing, Xiqian [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 28.01.2022 Date Revised 28.01.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1080/17476348.2021.1862653 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM318632578 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM318632578 | ||
| 003 | DE-627 | ||
| 005 | 20231225165747.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/17476348.2021.1862653 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1062.xml |
| 035 | |a (DE-627)NLM318632578 | ||
| 035 | |a (NLM)33297795 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Xing, Xiqian |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Impact of renal function on the prognosis of acute pulmonary embolism patients |b a systematic review and meta-analysis |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 28.01.2022 | ||
| 500 | |a Date Revised 28.01.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: We conduct a study to explore the influence of impaired renal function on prognosis in Acute pulmonary embolism (APE) patients | ||
| 520 | |a METHODS: A meta-analysis was performed using the EMBASE and PubMed databases for relevant publications reporting the impact of impaired renal function on the clinical outcomes in patients with APE | ||
| 520 | |a RESULTS: Eventually, 17 articles were included in our analysis. The results suggested that renal insufficiency (RI) is a predictor of poor prognosis in APE patients(short-term mortality: pooled OR = 2.83, 95%CI: 2.20-3.63; long-term mortality: pooled OR = 2.30, 95%CI: 1.72-3.08; adverse outcomes: pooled OR = 3.02, 95%CI: 2.60-3.51). The short-term and long-term mortality rates of APE patients with RI were both higher than those in patients without RI. In addition, acute kidney injury(AKI) could serve as a predictive factor of poor prognosis (pooled OR = 2.75, 95%CI: 2.45-3.08), and it doubles the overall mortality rate in APE patients. However, chronic kidney disease (CKD) did not predict poor prognosis in APE patients (pooled OR = 1.94, 95%CI: 0.99-3.81), although it could slightly increase the overall mortality rate in APE patients | ||
| 520 | |a CONCLUSIONS: RI and AKI could be included in the prognosis evaluation for APE, but the impact of CKD in APE patients has yet to be determined | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Systematic Review | |
| 650 | 4 | |a Acute pulmonary embolism | |
| 650 | 4 | |a acute kidney injury (AKI) | |
| 650 | 4 | |a chronic kidney disease (CKD) | |
| 650 | 4 | |a prognosis | |
| 650 | 4 | |a renal function | |
| 650 | 4 | |a renal insufficiency (RI) | |
| 700 | 1 | |a Liu, Jie |e verfasserin |4 aut | |
| 700 | 1 | |a Deng, Yishu |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Shuanglan |e verfasserin |4 aut | |
| 700 | 1 | |a Wei, Li |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Mei |e verfasserin |4 aut | |
| 700 | 1 | |a He, Xiaohua |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Bing |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Xiaoxian |e verfasserin |4 aut | |
| 700 | 1 | |a Yue, Qiaoning |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Jiao |e verfasserin |4 aut | |
| 700 | 1 | |a Teng, Zhaowei |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Expert review of respiratory medicine |d 2007 |g 16(2022), 1 vom: 05. Jan., Seite 91-98 |w (DE-627)NLM190765666 |x 1747-6356 |7 nnns |
| 773 | 1 | 8 | |g volume:16 |g year:2022 |g number:1 |g day:05 |g month:01 |g pages:91-98 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1080/17476348.2021.1862653 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 16 |j 2022 |e 1 |b 05 |c 01 |h 91-98 | ||