Epidemiological characterisation of asymptomatic carriers of COVID-19 in Colombia : a cross-sectional study

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..

INTRODUCTION: Asymptomatic carriers (AC) of the new SARS-CoV-2 represent an important source of spread for COVID-19. Early diagnosis of these cases is a powerful tool to control the pandemic. Our objective was to characterise patients with AC status and identify associated sociodemographic factors.

METHODS: Using a cross-sectional design and the national database of daily occurrence of COVID-19, we characterised both socially and demographically all ACs. Additional correspondence analysis and logistic regression model were performed to identify characteristics associated with AC state (OR, 95% CI).

RESULTS: 76.162 ACs (12.1%; 95% CI 12.0% to 12.2%) were identified, mainly before epidemiological week 35. Age≤26 years (1.18; 1.09 to 1.28), male sex (1.51; 1.40 to 1.62), cases imported from Venezuela, Argentina, Brazil, Germany, Puerto Rico, Spain, USA or Mexico (12.6; 3.03 to 52.5) and autochthonous cases (22.6; 5.62 to 91.4) increased the risk of identifying ACs. We also identified groups of departments with moderate (1.23; 1.13 to 1.34) and strong (19.8; 18.6 to 21.0) association with ACs.

CONCLUSION: Sociodemographic characteristics strongly associated with AC were identified, which may explain its epidemiological relevance and usefulness to optimise mass screening strategies and prevent person-to-person transmission.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:10

Enthalten in:

BMJ open - 10(2020), 12 vom: 07. Dez., Seite e042122

Sprache:

Englisch

Beteiligte Personen:

Teherán, Aníbal A [VerfasserIn]
Camero Ramos, Gabriel [VerfasserIn]
Prado de la Guardia, Ronald [VerfasserIn]
Hernández, Carolina [VerfasserIn]
Herrera, Giovanny [VerfasserIn]
Pombo, Luis M [VerfasserIn]
Avila, Albert Alejandro [VerfasserIn]
Flórez, Carolina [VerfasserIn]
Barros, Esther C [VerfasserIn]
Perez-Garcia, Luis [VerfasserIn]
Paniz-Mondolfi, Alberto [VerfasserIn]
Ramírez, Juan David [VerfasserIn]

Links:

Volltext

Themen:

Epidemiology
Infectious diseases
Journal Article
Virology

Anmerkungen:

Date Completed 21.12.2020

Date Revised 29.08.2023

published: Electronic

Citation Status MEDLINE

doi:

10.1136/bmjopen-2020-042122

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM318588501