Myositis : From classification to diagnosis

Copyright © 2020 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved..

Idiopathic inflammatory myopathies, or IIM, are a group of acquired diseases that affect the muscle to a certain extent, and may also affect other organs. They include dermatomyositis, which can affect the muscle eventualy, with a typical skin rash; inclusion body myositis, with a purely muscular expression resulting in a slow progressive deficit; and the former group of "polymyositis", a misnomer that actually includes other categories of IIM, such as immune-mediated necrotizing myopathies, with a severe muscle involvement often presents from the onset of the disease; antisynthetase syndrome, which combines muscle damage, joint involvement and a potentially life-threatening lung disease; and overlapping myositis, which combines muscle damage with other organs involvement connected to another autoimmune disease. The diagnosis of IIM is based on rigorous clinical examination and interrogation, electromyographic data and immunological testing for myositis specific antibodies. This antibody dosage must be extended or repeated if necessary to classify correctly the muscle disease under investigation, as the available tests may not perform well enough. Muscle biopsy, although very informative, is not anymore systematically recommended when the clinic and the antibodies are typical. However, some forms of IIM are sometimes difficult to classify; in these cases, muscle biopsy plays a crucial role in the precise etiological diagnosis.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:42

Enthalten in:

La Revue de medecine interne - 42(2021), 6 vom: 08. Juni, Seite 392-400

Sprache:

Französisch

Weiterer Titel:

Myosites : de la classification au diagnostic

Beteiligte Personen:

Fer, F [VerfasserIn]
Allenbach, Y [VerfasserIn]
Benveniste, O [VerfasserIn]

Links:

Volltext

Themen:

Anticorps spécifique des myosites
Antisynthétase
Antisynthetase
Autoantibodies
Dermatomyosite
Dermatomyositis
Inflammatory myopathy
Journal Article
Myopathie inflammatoire
Myosite
Myositis
Myositis-specific antibodies

Anmerkungen:

Date Completed 24.11.2021

Date Revised 24.11.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.revmed.2020.10.379

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM318152622