Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response

© 2020 Wiley Periodicals LLC..

Kidney transplant (KT) recipients are at an increased risk for severe COVID-19 because of their immunosuppressed state. A 42-year-old KT patient was diagnosed with COVID-19 three months after KT. Despite lymphopenia and several risk factors, he had a mild disease course. Nasopharyngeal real-time reverse transcriptase polymerase chain reaction for SARS-CoV-2 became negative 48 days after detection. SARS-CoV-2 IgG antibodies became negative after day 40. TTV DNA load increased with the onset COVID-19 and reduced after its resolution. This is the first report where TTV DNA load was measured during the course of COVID-19.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:23

Enthalten in:

Transplant infectious disease : an official journal of the Transplantation Society - 23(2021), 2 vom: 23. Apr., Seite e13524

Sprache:

Englisch

Beteiligte Personen:

Querido, Sara [VerfasserIn]
Calça, Rita [VerfasserIn]
Weigert, André [VerfasserIn]
Francisco, Diogo [VerfasserIn]
Adragão, Teresa [VerfasserIn]
Ana Pessanha, Maria [VerfasserIn]
Gomes, Perpétua [VerfasserIn]
Rodrigues, Luís [VerfasserIn]
Figueira, João M [VerfasserIn]
Cardoso, Conceição [VerfasserIn]
Machado, Domingos [VerfasserIn]

Links:

Volltext

Themen:

9PHQ9Y1OLM
Antibodies, Viral
COVID-19
Case Reports
DNA, Viral
Glucocorticoids
HU9DX48N0T
Immunoglobulin G
Immunoglobulin M
Immunosuppressive Agents
Kidney transplant
Mycophenolic Acid
Prednisolone
SARS-CoV-2
Tacrolimus
Torquetenovirus
WM0HAQ4WNM

Anmerkungen:

Date Completed 30.04.2021

Date Revised 31.07.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/tid.13524

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM317936514