Mineralocorticoid receptor blockade improves pulmonary hypertension and right ventricular function in bronchopulmonary dysplasia : a case report
2020 Cardiovascular Diagnosis and Therapy. All rights reserved..
Bronchopulmonary dysplasia (BPD) is a combined pulmonary vascular and parenchymal disease, representing the most common cause of chronic lung disease (CLD) in infancy. Pulmonary hypertension (PH) is frequently associated with BPD and-if persistent-substantially increases mortality. We report on a 4-month-old, former preterm infant with BPD, severe PH and right heart failure who greatly and rapidly improved clinical status and right ventricular (RV) function by means of blood biomarkers [N-terminal prohormone of brain natriuretic peptide (NT-pro-BNP), cardiac troponin T] and transthoracic echocardiography, following the addition of spironolactone and hydrochlorothiazide to the treatment regimen.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Cardiovascular diagnosis and therapy - 10(2020), 5 vom: 17. Okt., Seite 1686-1690 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Giagnorio, Roberto [VerfasserIn] |
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| Links: |
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| Themen: |
Bronchopulmonary dysplasia (BPD) |
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| Anmerkungen: |
Date Revised 24.11.2020 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.21037/cdt.2020.02.05 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM31791782X |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a 2020 Cardiovascular Diagnosis and Therapy. All rights reserved. | ||
| 520 | |a Bronchopulmonary dysplasia (BPD) is a combined pulmonary vascular and parenchymal disease, representing the most common cause of chronic lung disease (CLD) in infancy. Pulmonary hypertension (PH) is frequently associated with BPD and-if persistent-substantially increases mortality. We report on a 4-month-old, former preterm infant with BPD, severe PH and right heart failure who greatly and rapidly improved clinical status and right ventricular (RV) function by means of blood biomarkers [N-terminal prohormone of brain natriuretic peptide (NT-pro-BNP), cardiac troponin T] and transthoracic echocardiography, following the addition of spironolactone and hydrochlorothiazide to the treatment regimen | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Pulmonary hypertension (PH) | |
| 650 | 4 | |a bronchopulmonary dysplasia (BPD) | |
| 650 | 4 | |a case report | |
| 650 | 4 | |a hydrochlorothiazide (HCTZ) | |
| 650 | 4 | |a spironolactone | |
| 700 | 1 | |a Hansmann, Georg |e verfasserin |4 aut | |
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