Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan
Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Emerging infectious diseases - 26(2020), 12 vom: 29. Dez., Seite 3025-3029 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Murakami, Shin [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 04.12.2020 Date Revised 14.12.2020 published: Print Citation Status MEDLINE |
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| doi: |
10.3201/eid2612.203386 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM317868268 |
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| 100 | 1 | |a Murakami, Shin |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan |
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| 500 | |a Date Completed 04.12.2020 | ||
| 500 | |a Date Revised 14.12.2020 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Japan | |
| 650 | 4 | |a Rhinolophus cornutus | |
| 650 | 4 | |a SARS | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a bat sarbecovirus | |
| 650 | 4 | |a betacoronavirus | |
| 650 | 4 | |a coronavirus | |
| 650 | 4 | |a coronavirus disease | |
| 650 | 4 | |a respiratory infections | |
| 650 | 4 | |a severe acute respiratory syndrome coronavirus 2 | |
| 650 | 4 | |a viruses | |
| 650 | 4 | |a zoonoses | |
| 650 | 7 | |a Spike Glycoprotein, Coronavirus |2 NLM | |
| 650 | 7 | |a spike protein, SARS-CoV-2 |2 NLM | |
| 650 | 7 | |a Angiotensin-Converting Enzyme 2 |2 NLM | |
| 650 | 7 | |a EC 3.4.17.23 |2 NLM | |
| 700 | 1 | |a Kitamura, Tomoya |e verfasserin |4 aut | |
| 700 | 1 | |a Suzuki, Jin |e verfasserin |4 aut | |
| 700 | 1 | |a Sato, Ryouta |e verfasserin |4 aut | |
| 700 | 1 | |a Aoi, Toshiki |e verfasserin |4 aut | |
| 700 | 1 | |a Fujii, Marina |e verfasserin |4 aut | |
| 700 | 1 | |a Matsugo, Hiromichi |e verfasserin |4 aut | |
| 700 | 1 | |a Kamiki, Haruhiko |e verfasserin |4 aut | |
| 700 | 1 | |a Ishida, Hiroho |e verfasserin |4 aut | |
| 700 | 1 | |a Takenaka-Uema, Akiko |e verfasserin |4 aut | |
| 700 | 1 | |a Shimojima, Masayuki |e verfasserin |4 aut | |
| 700 | 1 | |a Horimoto, Taisuke |e verfasserin |4 aut | |
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| 773 | 1 | 8 | |g volume:26 |g year:2020 |g number:12 |g day:29 |g month:12 |g pages:3025-3029 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3201/eid2612.203386 |3 Volltext |
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