Physical Exercise as a Multimodal Tool for COVID-19 : Could It Be Used as a Preventive Strategy?

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus disease 2019 (COVID-19) is a novel coronavirus not previously recognized in humans until late 2019. On 31 December 2019, a cluster of cases of pneumonia of unspecified etiology was reported to the World Health Organization in China. The availability of adequate SARS-CoV-2 drugs is also limited, and the efficacy and safety of these drugs for COVID-2019 pneumonia patients need to be assessed by further clinical trials. For these reasons, there is a need for other strategies against COVID-19 that are capable of prevention and treatment. Physical exercise has proven to be an effective therapy for most chronic diseases and microbial infections with preventive/therapeutic benefits, considering that exercise involves primary immunological mediators and/or anti-inflammatory properties. This review aimed to provide an insight into how the implementation of a physical exercise program against COVID-19 may be a useful complementary tool for prevention, which can also enhance recovery, improve quality of life, and provide immune protection against SARS-CoV-2 virus infection in the long term. In summary, physical exercise training exerts immunomodulatory effects, controls the viral gateway, modulates inflammation, stimulates nitric oxide synthesis pathways, and establishes control over oxidative stress.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:17

Enthalten in:

International journal of environmental research and public health - 17(2020), 22 vom: 17. Nov.

Sprache:

Englisch

Beteiligte Personen:

Fernández-Lázaro, Diego [VerfasserIn]
González-Bernal, Jerónimo J [VerfasserIn]
Sánchez-Serrano, Nerea [VerfasserIn]
Navascués, Lourdes Jiménez [VerfasserIn]
Ascaso-Del-Río, Ana [VerfasserIn]
Mielgo-Ayuso, Juan [VerfasserIn]

Links:

Volltext

Themen:

31C4KY9ESH
COVID-19
Health care
Immune system
Inflammation
Journal Article
Nitric Oxide
Nitric oxide
Oxidative stress
Physical exercise
Review

Anmerkungen:

Date Completed 25.11.2020

Date Revised 18.12.2020

published: Electronic

Citation Status MEDLINE

doi:

10.3390/ijerph17228496

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM317798677