Effects of pine pollen wall on gut microbiota and biomarkers in mice with dyslipidemia
© 2020 John Wiley & Sons Ltd..
Pinus yunnanensis pollen is rich in various physiological functions. However, whether the pine pollen wall (PW) plays a beneficial role in the body has not been studied. In this work, we have analyzed its effects on the metabolism and gut microbiota of mouse models of dyslipidemia. We found that the intake of pine PW prevents the liver pathologic changes and reduce the concentrations of TNF-α, IL-6, TC, and high-density lipoprotein cholesterol. Moreover, it can regulate bile acid and fat metabolism, SCFAs content, and the structure of the gut microbiota. According to the change of carbohydrate metabolites, we speculated that cellulose should be the main component to play the above beneficial role, and sporopollenin cannot be utilized in the intestine. Therefore, we consider this study of great significance as it gives a description of biological effects of the pine PW and paves the road to its use in health products.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
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| Enthalten in: |
Phytotherapy research : PTR - 35(2021), 4 vom: 04. Apr., Seite 2057-2073 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Song, Xiao [VerfasserIn] |
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| Links: |
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| Themen: |
Biomarkers |
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| Anmerkungen: |
Date Completed 06.10.2023 Date Revised 06.10.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/ptr.6952 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM317775170 |
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| 520 | |a Pinus yunnanensis pollen is rich in various physiological functions. However, whether the pine pollen wall (PW) plays a beneficial role in the body has not been studied. In this work, we have analyzed its effects on the metabolism and gut microbiota of mouse models of dyslipidemia. We found that the intake of pine PW prevents the liver pathologic changes and reduce the concentrations of TNF-α, IL-6, TC, and high-density lipoprotein cholesterol. Moreover, it can regulate bile acid and fat metabolism, SCFAs content, and the structure of the gut microbiota. According to the change of carbohydrate metabolites, we speculated that cellulose should be the main component to play the above beneficial role, and sporopollenin cannot be utilized in the intestine. Therefore, we consider this study of great significance as it gives a description of biological effects of the pine PW and paves the road to its use in health products | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a gut microbiota | |
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| 650 | 4 | |a pine pollen wall | |
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| 700 | 1 | |a Ma, Ning |e verfasserin |4 aut | |
| 700 | 1 | |a Yin, Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Zhong, Micun |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Tong |e verfasserin |4 aut | |
| 700 | 1 | |a Shi, Lihua |e verfasserin |4 aut | |
| 700 | 1 | |a Geng, Yue |e verfasserin |4 aut | |
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