COVID-19 outcomes in UK centre within highest health and wealth band : a prospective cohort study
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ..
OBJECTIVES: To describe the characteristics and outcomes of hospitalised patients with COVID-19 from UK in the highest decile of health and gross regional products per capita.
DESIGN: Prospective cohort study.
SETTING: Recruited all adult inpatients with laboratory-confirmed COVID-19 symptoms admitted to a single Surrey centre between March and April 2020. Extensive demographic details were documented.
OUTCOME MEASURE: COVID-19 status of alive/dead and intensive care unit (ICU) status of yes/no.
PARTICIPANTS: Patients with COVID-19 from Surrey centre UK (n=429).
RESULTS: 429 adult inpatients (mean age 70±18 years; men 56.4%) were included in this study, of whom, 19.1% required admission to ICU and 31.9% died. Adverse outcomes were associated with age (OR with each decade of years: 1.78, 95% CI 1.53 to 2.11, p<0.001 for mortality); male gender (OR=1.08, 95% CI 0.72 to 1.63, p=0.72, present in 70.7%, of admissions to ICU versus 53% of other cases, p=0.004); cardiac disease (OR=3.43, 95% CI 2.10 to 5.63, p<0.001), diabetes mellitus (OR=2.37, 95% CI 1.09 to 5.17, p=0.028) and dementia (OR=5.06, 95% CI 2.79 to 9.44, p<0.001). There was no significant impact of ethnicity or body mass index on disease outcome.
CONCLUSIONS: Despite reports of worse outcomes in deprived regions, we show similar complication and mortality rates due to COVID-19 in an affluent and high life expectancy region.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
BMJ open - 10(2020), 11 vom: 16. Nov., Seite e042090 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ken-Dror, Gie [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 04.12.2020 Date Revised 30.03.2024 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1136/bmjopen-2020-042090 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM317667963 |
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| 245 | 1 | 0 | |a COVID-19 outcomes in UK centre within highest health and wealth band |b a prospective cohort study |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. | ||
| 520 | |a OBJECTIVES: To describe the characteristics and outcomes of hospitalised patients with COVID-19 from UK in the highest decile of health and gross regional products per capita | ||
| 520 | |a DESIGN: Prospective cohort study | ||
| 520 | |a SETTING: Recruited all adult inpatients with laboratory-confirmed COVID-19 symptoms admitted to a single Surrey centre between March and April 2020. Extensive demographic details were documented | ||
| 520 | |a OUTCOME MEASURE: COVID-19 status of alive/dead and intensive care unit (ICU) status of yes/no | ||
| 520 | |a PARTICIPANTS: Patients with COVID-19 from Surrey centre UK (n=429) | ||
| 520 | |a RESULTS: 429 adult inpatients (mean age 70±18 years; men 56.4%) were included in this study, of whom, 19.1% required admission to ICU and 31.9% died. Adverse outcomes were associated with age (OR with each decade of years: 1.78, 95% CI 1.53 to 2.11, p<0.001 for mortality); male gender (OR=1.08, 95% CI 0.72 to 1.63, p=0.72, present in 70.7%, of admissions to ICU versus 53% of other cases, p=0.004); cardiac disease (OR=3.43, 95% CI 2.10 to 5.63, p<0.001), diabetes mellitus (OR=2.37, 95% CI 1.09 to 5.17, p=0.028) and dementia (OR=5.06, 95% CI 2.79 to 9.44, p<0.001). There was no significant impact of ethnicity or body mass index on disease outcome | ||
| 520 | |a CONCLUSIONS: Despite reports of worse outcomes in deprived regions, we show similar complication and mortality rates due to COVID-19 in an affluent and high life expectancy region | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a public health | |
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| 700 | 1 | |a Russo, Cristina |e verfasserin |4 aut | |
| 700 | 1 | |a Sharma, Aarti |e verfasserin |4 aut | |
| 700 | 1 | |a Joy, Elizabeth |e verfasserin |4 aut | |
| 700 | 1 | |a John, Joshua |e verfasserin |4 aut | |
| 700 | 1 | |a Robin, Jonathan |e verfasserin |4 aut | |
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| 700 | 1 | |a Bentley, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Sharma, Pankaj |e verfasserin |4 aut | |
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