Profile of coronary artery disease in indian rural youth (< 35 yrs)
Copyright © 2020 Cardiological Society of India. Published by Elsevier B.V. All rights reserved..
AIMS: To study the risk factors, clinical and angiographic profile of Indian rural youth (under 35yrs) presenting with Premature Coronary Artery Disease (PCAD).
SUBJECTS: and Methods: The PCAD registry had 1628 patients who were aged below 35 years, of which 681 patients satisfied the entry criteria. The data was analysed by statistical software R version 3.5.0.
RESULTS: The study enrolled 681 patients after satisfying the entry criteria. The mean age of patients was 30.85 years. There were 405 (59.5%) aged between 30 and 35 yrs, 205 (30.1%) between 25 and 30 yrs, 64 (9.4%) between 20 and 25 yrs and 7 (1.0%) were aged less than 20 yrs. Majority of them were males, 617 (90.6%). Nearly 411 (60.4%) were smokers, 56patients (8.2%) were diabetics and 97 (14.2%) were hypertensives. Around 441 (64.8%) patients had low HDL cholesterol levels and 218 (32.0%) had elevated triglyceride levels. Abdominal obesity was seen in 443 (65.1%) patients. Most common clinical presentation was ST elevation myocardial infarction (STEMI) seen in 536 (78.7%) patients. Around 40% patients had recanalized/non obstructive/thrombotic/normal coronaries on coronary angiogram.
CONCLUSIONS: Conventional risk factors such as smoking, low HDL levels and abdominal obesity play a major role in the causation of premature coronary artery disease among the rural youth. Thrombotic milieu in the coronaries was commonly noted in coronary angiograms. Lack of awareness, combined with urbanisation of rural lifestyle could be responsible for increasing incidence of premature coronary artery disease in rural youth.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:72 |
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| Enthalten in: |
Indian heart journal - 72(2020), 5 vom: 19. Sept., Seite 394-397 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Patil, Rahul S [VerfasserIn] |
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| Links: |
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| Themen: |
Abdominal obesity |
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| Anmerkungen: |
Date Completed 11.05.2021 Date Revised 12.11.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ihj.2020.08.002 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM317566199 |
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| 245 | 1 | 0 | |a Profile of coronary artery disease in indian rural youth (< 35 yrs) |
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| 500 | |a Date Completed 11.05.2021 | ||
| 500 | |a Date Revised 12.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 Cardiological Society of India. Published by Elsevier B.V. All rights reserved. | ||
| 520 | |a AIMS: To study the risk factors, clinical and angiographic profile of Indian rural youth (under 35yrs) presenting with Premature Coronary Artery Disease (PCAD) | ||
| 520 | |a SUBJECTS: and Methods: The PCAD registry had 1628 patients who were aged below 35 years, of which 681 patients satisfied the entry criteria. The data was analysed by statistical software R version 3.5.0 | ||
| 520 | |a RESULTS: The study enrolled 681 patients after satisfying the entry criteria. The mean age of patients was 30.85 years. There were 405 (59.5%) aged between 30 and 35 yrs, 205 (30.1%) between 25 and 30 yrs, 64 (9.4%) between 20 and 25 yrs and 7 (1.0%) were aged less than 20 yrs. Majority of them were males, 617 (90.6%). Nearly 411 (60.4%) were smokers, 56patients (8.2%) were diabetics and 97 (14.2%) were hypertensives. Around 441 (64.8%) patients had low HDL cholesterol levels and 218 (32.0%) had elevated triglyceride levels. Abdominal obesity was seen in 443 (65.1%) patients. Most common clinical presentation was ST elevation myocardial infarction (STEMI) seen in 536 (78.7%) patients. Around 40% patients had recanalized/non obstructive/thrombotic/normal coronaries on coronary angiogram | ||
| 520 | |a CONCLUSIONS: Conventional risk factors such as smoking, low HDL levels and abdominal obesity play a major role in the causation of premature coronary artery disease among the rural youth. Thrombotic milieu in the coronaries was commonly noted in coronary angiograms. Lack of awareness, combined with urbanisation of rural lifestyle could be responsible for increasing incidence of premature coronary artery disease in rural youth | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Abdominal obesity | |
| 650 | 4 | |a Low HDL | |
| 650 | 4 | |a Premature coronary artery disease | |
| 650 | 4 | |a Prospective observational study | |
| 650 | 4 | |a Rural youth | |
| 650 | 4 | |a Smoking | |
| 650 | 4 | |a Under 35years | |
| 700 | 1 | |a Shetty, Laxmi H |e verfasserin |4 aut | |
| 700 | 1 | |a Krishnan, Shanmugam |e verfasserin |4 aut | |
| 700 | 1 | |a Trivedi, Anindya Sundar |e verfasserin |4 aut | |
| 700 | 1 | |a Raghu, T R |e verfasserin |4 aut | |
| 700 | 1 | |a Manjunath, C N |e verfasserin |4 aut | |
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