Simultaneous determination of melatonin and trans-resveratrol in wine by dispersive liquid-liquid microextraction followed by HPLC-FLD
Copyright © 2020 Elsevier Ltd. All rights reserved..
The discovery of melatonin (Mel) in wines triggered a new interest in the paradigm of health benefits and wine consumption, usually ascribed to trans-resveratrol (trans-RSV). In this context, a dispersive liquid-liquid microextraction for the analysis of Mel and trans-RSV in wines by LC-FLD was developed. A 26-1 factorial design was used to identify the significant variables (p < 0.05) and Central Composite Design was used to achieve the optimal conditions: 300 µL of chloroform (extracting solvent), 1500 µL of acetonitrile (disperser solvent) and 1500 mg of NaCl (ionic strength). Excellent linearity (R2 > 0.9999), repeatability (<3.55%), and accuracy (<7.18%) were obtained using a blank matrix and recoveries (>91.9%) using wines. The method was successfully applied to the analyses of Mel (0.63-7.44 ng mL-1) and trans-RSV (169-2616 ng mL-1) in different wine varieties. Comparison with literature point the overall advantages of the new method.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:339 |
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| Enthalten in: |
Food chemistry - 339(2021) vom: 01. März, Seite 128091 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Viegas, Olga [VerfasserIn] |
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| Links: |
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| Themen: |
Green chemistry |
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| Anmerkungen: |
Date Completed 10.12.2020 Date Revised 14.12.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.foodchem.2020.128091 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM317210130 |
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| 245 | 1 | 0 | |a Simultaneous determination of melatonin and trans-resveratrol in wine by dispersive liquid-liquid microextraction followed by HPLC-FLD |
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| 500 | |a Date Revised 14.12.2020 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 Elsevier Ltd. All rights reserved. | ||
| 520 | |a The discovery of melatonin (Mel) in wines triggered a new interest in the paradigm of health benefits and wine consumption, usually ascribed to trans-resveratrol (trans-RSV). In this context, a dispersive liquid-liquid microextraction for the analysis of Mel and trans-RSV in wines by LC-FLD was developed. A 26-1 factorial design was used to identify the significant variables (p < 0.05) and Central Composite Design was used to achieve the optimal conditions: 300 µL of chloroform (extracting solvent), 1500 µL of acetonitrile (disperser solvent) and 1500 mg of NaCl (ionic strength). Excellent linearity (R2 > 0.9999), repeatability (<3.55%), and accuracy (<7.18%) were obtained using a blank matrix and recoveries (>91.9%) using wines. The method was successfully applied to the analyses of Mel (0.63-7.44 ng mL-1) and trans-RSV (169-2616 ng mL-1) in different wine varieties. Comparison with literature point the overall advantages of the new method | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Green chemistry | |
| 650 | 4 | |a Melatonin | |
| 650 | 4 | |a Method validation | |
| 650 | 4 | |a Microextraction | |
| 650 | 4 | |a Response surface methodology | |
| 650 | 4 | |a Trans-resveratrol | |
| 650 | 4 | |a Wine | |
| 650 | 7 | |a Solvents |2 NLM | |
| 650 | 7 | |a Melatonin |2 NLM | |
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| 650 | 7 | |a Resveratrol |2 NLM | |
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| 700 | 1 | |a Esteves, Cristina |e verfasserin |4 aut | |
| 700 | 1 | |a Rocha, Janete |e verfasserin |4 aut | |
| 700 | 1 | |a Melo, Armindo |e verfasserin |4 aut | |
| 700 | 1 | |a Ferreira, Isabel M P L V O |e verfasserin |4 aut | |
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