Heavy metal and pesticide levels in dairy products : Evaluation of human health risk
Copyright © 2020 Elsevier Ltd. All rights reserved..
Cattle milk's health benefits can be compromised by the presence of contaminants. The levels of cadmium, copper, lead and zinc, and residues of dichlorodiphenyldichloroethylene (DDE), dichlorodiphenyldichloroethane (DDD), dichlorodiphenyltrichloroethane (DDT) were determined in soil, milk and cheese samples collected from cow farms from 3 Romanian areas with industrial and agriculture tradition. A new methodology was applied for the determination of the corrected estimated daily intake (cEDI) corresponding to the aggregate dietary exposure. For the risk assessment, we calculated the source hazard quotient (HQs) for each contaminant and the adversity specific hazard index (HIA). Cadmium, copper, lead and zinc, and the sum of DDT levels in soil samples were below maximum residue levels (MRLs). The MRLs of lead and DDD were exceeded in milk and cheese samples from all the 3 areas. The MRLs of copper and zinc were exceeded in cheese samples from area 2 and 3. HQs >10 for lead indicates increased risk, while HQ > 1 for copper and sum of DDT indicates moderate risk for both milk and cheese. By calculating the HIA, we identified a moderate and increase risk for nephrotoxicity, hepatotoxicity, hematotoxicity, cardiotoxicity and reproduction toxicity after consumption of the dairy products from the 3 areas.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:146 |
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| Enthalten in: |
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 146(2020) vom: 01. Dez., Seite 111844 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Năstăsescu, Valentin [VerfasserIn] |
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| Links: |
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| Themen: |
Dairy products |
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| Anmerkungen: |
Date Completed 11.06.2021 Date Revised 11.06.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.fct.2020.111844 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM317206095 |
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| 520 | |a Copyright © 2020 Elsevier Ltd. All rights reserved. | ||
| 520 | |a Cattle milk's health benefits can be compromised by the presence of contaminants. The levels of cadmium, copper, lead and zinc, and residues of dichlorodiphenyldichloroethylene (DDE), dichlorodiphenyldichloroethane (DDD), dichlorodiphenyltrichloroethane (DDT) were determined in soil, milk and cheese samples collected from cow farms from 3 Romanian areas with industrial and agriculture tradition. A new methodology was applied for the determination of the corrected estimated daily intake (cEDI) corresponding to the aggregate dietary exposure. For the risk assessment, we calculated the source hazard quotient (HQs) for each contaminant and the adversity specific hazard index (HIA). Cadmium, copper, lead and zinc, and the sum of DDT levels in soil samples were below maximum residue levels (MRLs). The MRLs of lead and DDD were exceeded in milk and cheese samples from all the 3 areas. The MRLs of copper and zinc were exceeded in cheese samples from area 2 and 3. HQs >10 for lead indicates increased risk, while HQ > 1 for copper and sum of DDT indicates moderate risk for both milk and cheese. By calculating the HIA, we identified a moderate and increase risk for nephrotoxicity, hepatotoxicity, hematotoxicity, cardiotoxicity and reproduction toxicity after consumption of the dairy products from the 3 areas | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Dairy products | |
| 650 | 4 | |a Food safety | |
| 650 | 4 | |a Heavy metals | |
| 650 | 4 | |a Pesticides | |
| 650 | 4 | |a Risk assessment | |
| 650 | 7 | |a Metals, Heavy |2 NLM | |
| 650 | 7 | |a Pesticide Residues |2 NLM | |
| 650 | 7 | |a Pesticides |2 NLM | |
| 650 | 7 | |a Soil Pollutants |2 NLM | |
| 700 | 1 | |a Mititelu, Magdalena |e verfasserin |4 aut | |
| 700 | 1 | |a Goumenou, Marina |e verfasserin |4 aut | |
| 700 | 1 | |a Docea, Anca Oana |e verfasserin |4 aut | |
| 700 | 1 | |a Renieri, Elisavet |e verfasserin |4 aut | |
| 700 | 1 | |a Udeanu, Denisa Ioana |e verfasserin |4 aut | |
| 700 | 1 | |a Oprea, Eliza |e verfasserin |4 aut | |
| 700 | 1 | |a Arsene, Andreea Letitia |e verfasserin |4 aut | |
| 700 | 1 | |a Dinu-Pîrvu, Cristina Elena |e verfasserin |4 aut | |
| 700 | 1 | |a Ghica, Manuela |e verfasserin |4 aut | |
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